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Grants FY15-16

NMRC

  • “Detection and quantitation of post-surgical fibrosis with biophotonic imaging technology”.
    A/Prof Tina Wong; S$245,983.00

  • “Optimization of SELENA - An automated, real time detection tool for early detection of diabetic retinopathy”.
    Prof Wong Tien Yin; S$208,000.00

  • “Analysis of oxidative stress in cultured and diseased human corneal endothelial cells”.
    A/Prof Jodhbir Mehta; S$674,900.00

  • “Development of a layer by layer nanoparticle sustained delivery system for nucleic acid therapeutics”.
    A/Prof Tina Wong; S$1,721,990.30

  • “The Singapore Chinese eye study 2 (SCES-2) – Prospective cohort study of 6-year incidence, risk factors, and impact of major age-related eye diseases”.
    A/Prof Cheng Ching-Yu; S$1,499,900.00

  • “Characterizing the role of CACNA1 in exfoliation syndrome and glaucoma”.
    Prof Aung Tin; S$1,375,720.00

  • “Whole exome sequencing to identify actionable mutations causative of primary angle closure glaucoma”.
    Prof Aung Tin; S$1,442,100.00

  • “The clinical and economic effectiveness of extending diabetic eye screening in Singapore”.
    Prof Ecosse Lamoureux; S$1,425,279.35

  • “Characterizing the role of iris surface features in iris sponginess and their relevance to angle-closure glaucoma”.
    A/Prof Cheng Ching-Yu; S$744,630.26

  • “Investigating the prevalence and impact of vision impairment, hearing loss and dual sensory impairment in residential care facilities in Singapore”.
    Dr Ryan Man; S$199,521.00

  • “The glaucoma initial treatment study: Comparing the effectiveness of selective laser trabeculoplasty with topical medication.  A multi-centre, prospective and randomized controlled clinical trial”.
    Adj A/Prof Shamira Perera; S$930,818.00

  • “The Asia primary tube versus trab (TVT) study”.
    Adj A/Prof Ho Ching Lin; S$2,100,168.00

  • “The use of atropine 0.01% in the prevention and progression of myopia: ATOM 3”.
    Adj A/Prof Audrey Chia; S$ 1,933,306.17

  • “Clinical, mechanical and histological characterization of trabecular meshwork in ocular hypertensive primates - Exploring mechanical strain in glaucoma”.
    Dr Baskaran Mani; S$374,829.00

  • “Investigating the role of inflammation in primary angle closure glaucoma”.
    Dr Monisha Nongpiur; S$374,695.00


A*Star/ Duke-NUS/ MOH/ Others

  • “Enhanced angle closure glaucoma risk assessment system (AGAR+)”.
    Prof Aung Tin; S$625,000.00

  • “Development of a smart, thermo-sensitive and bio-degradable hydrogel as an internal tamponading agent during vitreo-retinal surgery”.
    Dr Amutha Barathi Veluchamy; S$170,922.00

  • “Genetics of primary open angle glaucoma (POAG) in populations of African Ancestry”.
    Prof Michael Hauser; S$300,000.00

  • “Exploring the potential diagnostic value of retinal microvascular morphology in pediatric kawasaki disease”.
    Dr Queenie Li Lingjun; S$30,025.00

  • “Randomized controlled trial of lutein as a novel neuroprotective adjunctive therapy to improve visual outcome of rhegmatogenous retinal detachment (LUNAR Trial)”.
    Dr Ning Cheung; S$300,000.00

  • “Continuation of ATX in glaucoma- ATX inhibitor study in Dutch belted rabbits”.
    Dr Amutha Barathi Veluchamy; S$40,798.21

  • “Influence of severity of myopic maculopathy on efficacy of aflibercept treatment in eyes with choroidal neovascularization (mCNV) secondary to pathologic myopia”.
    A/Prof Gemmy Cheung; S$33,375.66

  • “New ophthalmic antifungal, DE-109”.
    Prof Roger Beuerman; S$134,710.24

  • “Myopia 1: Sustained release formulation for atropine delivery”.
    Prof Roger Beuerman; S$51,360.00

  • “Evaluating a novel eye care model for visually impaired people in various communities in Singapore: A pilot study”.
    Dr Anna Tan; S$20,000.00

  • “Dielectric fresnel zone plate lens: Enabling submicron resolution femtosecond laser for the next generation corneal refractive surgery”.
    A/Prof Jodhbir Mehta; S$22,000.00


SingHealth

  • “Investigating ethnic variations of corneal rigidity in Asians and its role in glaucoma”.
    Dr Jacqueline Chua; S$110,100.00

  • “Discrete event simulation of a primary angle closure glaucoma model in Singapore”.
    Dr Hla Myint Htoon; S$50,000.00

  • “Evaluation of immune response and the role of TEM cells in the pathogenesis of a chronic eye model”.
    Dr Hou Ai Hua; S$149,738.56

  • “Evaluation of corneal endothelial cell injection therapy for the treatment of Fuchs corneal endothelial dystrophy”.
    Dr Gary Peh; S$149,950.00

  • “Evaluation of a novel treatment for presbyopia, scleral Er:YAG laser procedure, on its feasibility, optimization and wound healing profiles”.
    Dr Liu Yu-Chi; S$50,000.00

  • “Natural phenolic compounds for durable antimicrobial contact lens wears”.
    Dr Chetna Dhand; S$50,000.00

  • “Reduction of post-surgical fibrosis in the SPARC-and Hevin-deficient conjunctiva by interleukin-5 inhibition”.
    Dr Seet Li Fong; S$149,998.79

  • “Engineering corneal stromal keratocytes from dental stem cells for cell replacement therapy to treat corneal opacities”.
    Dr Gary Yam; S$150,000.00


Commercial

  • “The efficacy and safety of bimatoprost SR in patients with open-angle glaucoma or ocular hypertension”.
    Prof Aung Tin; S$117,484.10

  • “Clinical outcomes comparison between visumax flocket and LDV pocket for implantation of the raindrop corneal inlay for the correction of presbyopia”.
    A/Prof Jodhbir Mehta; S$59,621.58

  • “Safety and efficacy of abicipar pegol (AGN-150998) in patients with neovascular age-related macular degeneration”.
    A/Prof Ian Yeo; S$437,752.25

  • “A two-year, randomized, double-masked, multicenter, two-arm study comparing the efficacy and safety of rth258 6 mg versus aflibercept in subjects with neovascular age-related macular degeneration”.
    A/Prof Gemmy Cheung; S$158,263.05

  • “A multiple-center, investigator/subject masked, adaptive, multiple-ascending dose, randomized, placebo-controlled, parallel study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of RO5093151 following 7 days administration in patients with primary open angle glaucoma or ocular hypertension”.
    Prof Aung Tin; S$85,065.39

  • “New ophthalmic antifungal, DE-109”.
    Prof Roger Beuerman; S$352,827.59

  • “Glaucoma HFA / OCT specificity study”.
    Prof Aung Tin; S$46,428.21

  • “Myopia-1: Sustained release formulation for atropine delivery”.
    Prof Roger Beuerman; S$159,175.00