Secukinumab belongs to a class of medicines called biologics. Biologics are genetically-engineered proteins. Secukinumab works by blocking the activity of a protein called interleukin (IL) 17A.IL-17A levels are increased in diseases such as psoriasis, psoriatic arthritis and ankylosing spondylitis. Secukinumab blocks IL-17A and helps to reduce the activity of the immune system and the symptoms of the diseases.
It may be used alone or together with other DMARDs.
Common side effects include:
Majority of these effects tend to resolve by themselves. Inform your doctor if any side effects persist, if you are unable to tolerate them or the side effects become serious.
Secukinumab may reduce your body's ability to fight against infection. You should consult a doctor immediately if you develop a fever or feel unwell. Inform the doctor whom you consult that you are taking Secukinumab as the medication may need to be stopped while you are having an infection.
Rare but serious side-effects include:
The symptoms of a drug allergy include one or more of the following:
If you experience any of these symptoms, you should stop your medication and see your doctor immediately.
Inform your healthcare professional if:
Let your doctor or dentist know that you are taking Secukinumab, as it may increase the risk of infection after a surgical procedure.
Avoid eating raw. undercooked or half-cooked food.
Secukinumab may interact with other medications or supplements that you are taking. These include:
Inform the doctor. pharmacist or specialty nurse before starting on a new medication or supplement.
Pneumococcal, influenza (flu) and Hepatitis B vaccinations are safe and may be given if required. Avoid live vaccines such as MMR (measles, mumps and rubella). OPV (oral polio vaccine). yellow fever or BCG (tuberculosis). Discuss with your doctor before receiving any vaccines.
If you miss a dose, inject it as soon as you remember. Talk to your doctor to discuss when the next dose should be given.
Store in the refrigerator at 2 to 8°C. Do not freeze. Keep in original packaging to protect it from light. Keep this medication away from children.
You may throw this injection away along with the used needles Into a metal tin or thick plastic container (eg. detergent bottles). You can also buy a container specially designed to throw sharp items, known as a sharps box, to prevent any injuries due to the needles.
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