Dr Htoon Hla Myint

​Dr Hla Myint Htoon, is a clinical outcomes research scientist. His work with SERI entails statistical and health economic evaluation research work for clinical outcomes.

• PhD (2007)
• BDS (1975)

• Member (Statistical Advisor), Institutional Animal Care and Use Committee, SingHealth (2016 – present)
• Statistical Advisor, Education Research Committee, Singapore National Eye Centre (2016 – present)
• Editorial Board Member (Statistical Advisor), Proceedings Journal Editorial Board, Singapore General Hospital (2013 – present)

• ​Development of Glaucoma Progression Application Tool Using a Modelling Approach (2017 – 2020)
• Discrete Event Simulation of a Primary Angle Closure Glaucoma Model in Singapore (2015 – 2021)
• Development of a Novel Utility Measure Using Discrete Choice Experiments to Assess the Impact of Glaucoma Treatments from the Patient’s Perspective (2015 – 2018)
• Development of Glaucoma Utility Index (GUI-S) in Singapore (2009 – 2013)

1. Au Eong JTW, Low JR, Fenwick EK, Htoon HM, Perera SA, Wong TT, Lamoureux EL, Man REK. Effect of Combined Cataract and Minimally Invasive Glaucoma Surgeries on Glaucoma-specific Quality of Life. J Clin Med. 2026 Feb 4;15(3):1215.

2. Chong RS, Sim B, Htoon HM, Chia A. Effect of Ocular Magnification Correction on Measurements of Macula Ganglion Cell Complex in Myopic Children. Am J Ophthalmol. 2026 Jan;281:284-296.

3. Tan ACS, Peterson CL, Htoon HM, Tan LLY, Tan Y, Sim KT, Ong L, Tan ZK, Heng SH, Yeo IYS, Wong TY, Cheung G, Man R, Fenwick EK, Lamoureux E. Development and Validation of Performance-based Assessment of Daily Living Tasks in Age-related Macular Degeneration. Transl Vis Sci Technol. 2024 Jun 3;13(6):9.

4. Woo JH, Arundhati A, Chee SP, Tong W, Li L, Ti SE, Htoon HM, Choo JQH, Tan D, Mehta JS. Endothelial Keratoplasty with Anterior Chamber Intraocular Lens Versus Secondary Posterior Chamber Intraocular Lens. Br J Ophthalmol. 2022 Feb;106(2):203-210.

5. Lanca C, Sun CH, Chong R, Wong YL, Nongpiur ME, Htoon HM, Thakur S, Quek DQY, Cheng CY, Hoang QV, Sabanayagam C, Saw SM, Wong CW. Visual Field Defects and Myopic Macular Degeneration in Singapore Adults with High Myopia. Br J Ophthalmol. 2022 Oct;106(10):1423-1428.

6. Ang M, Farook M, Htoon HM, Mehta JS. Randomised Clinical Trial Comparing Femtosecond LASIK and Small-incision Lenticule Extraction. Ophthalmology. 2020;127(6):724-730.

7. Foo LL, Htoon HM, Farooqui SZ, Chia A. Part-time Use of 1% Atropine Eye Drops for Prevention of Myopia Progression in Children. Int Ophthalmol. 2020 Apr 7. [Epub ahead of print]

8. Narayanaswamy A, Baskaran M, Tun TA, Htoon HM, Aung T. Effect of Pharmacological Pupil Dilatation on Angle Configuration in Untreated Primary Angle Closure Suspects: A Swept Source Anterior Segment Optical Coherence Tomography Study. J Glaucoma. 2020 Mar 27. [Epub ahead of print

9. Fan KR, Baskaran M, Nongpiur ME, Htoon HM, de Leon JMS, Perera SA, Belkin M, Aung T. Investigating the Neuroprotective Effect of Copolymer-1 in Acute Primary Angle Closure – Interim Report of a Randomised Placebo-controlled Double-masked Clinical Trial. Acta Ophthalmol. 2019 Sep;97(6):e827-e832.

10. Mayandi V, Sridhar S, Fazil MHUT, Goh ETL, Htoon HM, Orive G, Choong YK, Saravanan R, Beuerman RW, Barkham TMS, Yang L, Baskaran M, Jhanji V, Loh XJ, Verma NK, Lakshminarayanan R. Protective Action of Linear Polyethylenimine Against Staphylococcus Aureus Colonization and Exaggerated Inflammation in vitro and in vivo. ACS Infect Dis. 2019 Aug 9;5(8):1411-1422. doi:10.1021/acsinfecdis.9b00102. Epub 2019 Jun 5. PubMed PMID: 31099239.

11. Yam GH, Seah X, Yusoff NZBM, Setiawan M, Wahlig S, Htoon HM, Peh GSL, Kocaba V, Mehta JS. Characterisation of Human Transition Zone Reveals a Putative Progenitor-enriched Niche of Corneal Endothelium. Cells. 2019 Oct 12;8(10). pii: E1244. doi: 10.3390/cells8101244. PubMed PMID: 31614883; PubMed Central PMCID:PMC6829622.

12. Chua D, Htoon HM, Lim L, Chan CM, Mehta JS, Tan DTH, Rosman M. Eighteen-year Prospective Audit of LASIK Outcomes for Myopia in 53 731 eyes. Br J Ophthalmol.2019 Sep;103(9):1228-1234. doi:1136/bjophthalmol-2018-312587. Epub 2018 Oct24. PubMed PMID: 30355717

13. Narayanaswamy A, Baskaran M, Perera SA, Nongpiur ME, Htoon HM, Tun TA, Wong TT, Goh D, Su DH, Chew PT, Ho CL, Aung T. Argon Laser Peripheral Iridoplasty for Primary Angle-closure Glaucoma: A Randomised Controlled Trial. Ophthalmology. 2016 Mar; 123(3):514-21

14. Natarajan JV, Darwitan A, Barathi VA, Ang M, Htoon HM, Boey F, Tam KC, Wong TT, Venkatraman SS. Sustained Drug Release in Nanomedicine: A Long-acting Nanocarrier-based Formulation for Glaucoma. ACS Nano. 2014 Aug; 4(4):303-9

15. Wong MH, Husain R, Ang BC, Gazzard G, Foster PJ, Htoon HM, Wong TT, Oen FT, Khaw PT, Seah SK, Aung T. The Singapore 5-Fluorouracil Trial: Intraocular Pressure Outcomes at 8 Years. Ophthalmology 2013 Jun;120(6):1127-34

16. Anshu A, Parthasarathy A, Mehta JS, Htoon HM, Tan DT. Outcomes of Therapeutic Deep Lamellar Keratoplasty and Penetrating Keratoplasty for Advanced infectious keratitis: A Comparative Study. Ophthalmology. 2009 Apr; 116(4):615-2315

17. Wong TT, Khaw PT, Aung T, Foster PJ, Htoon HM, Oen FT, Gazzard G, Husain R, Devereux JG, Minassian D, Tan SB, Chew PT, Seah SK. The Singapore 5-Fluorouracil Trabeculectomy Study: Effects on Intraocular Pressure Control and Disease Progression at 3 Years. Ophthalmology. 2009 Feb;116(2):175-84 Ophthalmology. 2009 Jul; 116(7): 1391

18. Han DC, Mehta JS, Por YM, Htoon HM, Tan DT. Comparison of Outcomes of Lamellar Keratoplasty and Penetrating Keratoplasty in Keratoconus. Am J Ophthalmol. 2009 Nov; 148(5):744-751. Ophthalmology. 2009 Jul; 116(7): 1391

19. Tan DT, Janardhanan P, Zhou H, Chan YH, Htoon HM, Ang LP, Lim LS. Penetrating Keratoplasty in Asian Eyes: The Singapore Corneal Transplant Study. Ophthalmology. 2008 Jun; 115(6):975-982. 1391

20. Htoon HM, Peng LL, Huak CY. Assessment Criteria for Compliance with Oral Hygiene: Application of ROC Analysis. Oral Health Prev Dent. 2007; 5(2):83-8. 13