Prof Ecosse Lamoureux

Prof Ecosse Lamoureux is a tenured Professor with Duke-NUS Medical School and hold professorial appointments with the National University of Singapore (Ophthalmology) and University of Melbourne (Medicine, Dentistry and Health Sciences). He undertakes his clinical research with the Singapore Eye Research Institute (SERI), where he has developed a nationally competitive population health research (PHR) program. He is the Director of Population Health and Epidemiology at SERI and leads a translational, clinical, and population health research programme focused on improving outcomes for individuals with sensory impairment. He is the Principal Investigator of PIONEER (The PopulatION HEalth and Age-Related SEnsory Decline PRofile), a large, ongoing, multi-ethnic population-based cohort study that examines the clinical, biological, and psychosocial characteristics of older Singaporeans to better understand the burden, consequences, and underlying mechanisms of age-related sensory decline. He also leads the patient-centred outcomes research component of SEED (Singapore Epidemiology of Eye Diseases), one of the world's largest population-based eye studies, contributing significantly to the understanding of the economic, social, and personal burden of vision impairment and ocular diseases in Singapore. To date, his overall research activities have attracted over SG$40 million in competitive grant and he has ~500 publications in top international journals, with a current H and i10-indices of 87 and 404, respectively.

• PhD (2001)
• MApplSc (1996)
• GradDip (1992)
• BEd (1992)

• Professorial Fellow (Adjunct), Department of Surgery and Medicine, University of Melbourne, Australia (2018 – Present)
• Professor, Department of Ophthalmology, National University of Singapore (2015 – Present)
• Professor, Health Services and Systems Research, Duke-NUS Medical School (2015 – Present)

• Asia-Pacific Academy of Ophthalmology (APAO) Achievement Award (2017)
• APAO Outstanding Service in Prevention of Blindness Award (2015)
• Senior Research Fellowship-Level B, NHMRC (2013 – 2015)
• Career Development Award Fellowship, NHMRC (2009 – 2012)
• Public Health Postdoctoral Fellowship, NHMRC (2005 – 2009)

• Validation of the VISually Independent test battery Of NeuroCOGnition (VISION-Cog): A Novel Tool to Assess Cognitive Impairment in Older Adults with Visual Impairment (2026 – 2029)
• Integrating PIONEER and TRUST Data to Advance Healthy Ageing: A Linked Data Approach to Understanding Sensory and Cognitive Decline, Fracture Burden, and Cardiovascular Risk in Older Adults in Singapore (2026 – 2027)
• Revolutionising the Assessment of Quality of Life in Diabetes Using Item Banking and Computerised Adaptive Testing Systems (2021 – 2024)
• ​Computerized Adaptive Testing (CAT) Technologies to Improve Patient-provider Experience and Healthcare Outcomes for Patients (2019 – 2020)
• An Intensive, Practical, and Personalized Care Planning to Improve Glycemic Control, Clinical, Ocular, and Patient Centred Outcomes in Poorly Controlled Patients with Diabetic Retinopathy (2018 – 2022)
• TAAP: Translational Asian Age-related Macular Degeneration Program (2018 –2022)
• Optimising the Assessment of Quality of Life in Glaucoma using Item Bank and Computer Adaptive Testing Systems (2018 – 2020)
• Application and Evaluation of an Artificial Intelligence Deep Learning System to Detect Referable and Sight-threatening Retinal Diseases in the Singapore Integrated Diabetic Retinopathy Screening Programme (SiDRP): Screening Performance and Cost-effectiveness Analysis (2018 – 2020)
• An Innovative and Patient-Centric Research Program Targeting the Ageing Singaporeans: The PRevention of and interVentIon for eye Diseases in the Elderly [PROVIDE] Programme (2017 – 2021)
• Visually-disabling Pathologic Myopia in the SEED and SCORM High Myopia Cohorts: Longitudinal Changes, Novel Biomarkers and Impact on Health Related Quality of Life (2017 – 2020)
• Development of a Novel Utility Measure using Discrete Choice Experiments to Assess the Impact of Glaucoma Treatments from the Patient’s Perspective (2017 – 2020)
• The Singapore Diabetes Complications Study: Closing the Screening-referral Uptake Loop for Diabetic Retinopathy, Nephropathy, and Foot Complications (2016 – 2020)
• The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore (2016 – 2020)

1. Peng Q, Xue CC, Chua K, Li H, Nusinovici S, Soh ZD, Gupta P, Leem AY, Yu MCY, Sabanayagam C, Rim TH, Zhu Z, Lamoureux EL, Cheng CY. Retinal Biological Age Correlates with Bone Mineral Density and Fracture Risk Score and Predicts Incident Osteoporosis. PLOS Digit Health. 2026 May 14;5(5):e0001360.
2. Jha D, Zhou Y, Praveen AD, Galliker ES, Gupta P, Lamoureux EL, Hong N, Rhee Y, Pálsson H, Ferguson SJ, Helgason B. DXA-derived Biofidelic Finite Element Models for Quantifying the Efficacy of Hip Protectors. JBMR Plus. 2026 Apr 14;10(6):ziag067.
3. Yee H, Wong CMJ, Gupta P, Thakur S, Fenwick E, Lamoureux EL, Man REK. Prevalence, Risk Determinants, and Burden of Undiagnosed Age-related Eye Diseases Among Older Asian Adults. JAMA Ophthalmol. 2026 Jan 1;144(1):23-32.
4. Nooteboom I, Fenwick EK, Man REK, Wong JCM, Yeo Sheng Yep B, Gao EY, Kye Jyn Tan B, Yee H, Ng JH, Wei Yang Teo N, Forde C, Lamoureux EL, Gupta P. Elucidating the Burden of Dual-sensory Impairment in Community-based Older Individuals in a Multi-ethnic Society. Sci Rep. 2026 Apr 2.
5. Grgic J, Tey SL, Huynh DTT, Low YL, Pedisic Z, Schaller N, Wazny VK, Wang W, Saito Y, Rannan-Eliya RP, Ghattas H, Chaaya M, de Leon CM, Gupta P, Lamoureux EL, Subramaniam M, Abdin E, Malhotra R, Chan A, Tumenbayar B, Luvsandavaajav O, Enkhtuvshin B, Mansor N, Awang H, Maier AB. Asian Reference Values for Handgrip Strength, Gait Speed, Five-times-sit-to-stand Test, Muscle Mass and Calf Circumference. J Cachexia Sarcopenia Muscle. 2026 Feb;17(1):e70216.
6. Au Eong JTW, Low JR, Fenwick EK, Htoon HM, Perera SA, Wong TT, Lamoureux EL, Man REK. Effect of Combined Cataract and Minimally Invasive Glaucoma Surgeries on Glaucoma-specific Quality of Life. J Clin Med. 2026 Feb 4;15(3):1215.
7. Piccoli G, Fenwick EK, Bucceri V, Lamoureux EL, Tagliabue E, Nucci P, Vujosevic S. Impact of Vision Impairment and Microperimetry Parameters on Quality of Life in Patients with Center-involving Diabetic Macular Edema. Ophthalmol Sci. 2025 Nov 10;6(2):101001. 2026 Feb.
8. Zhang Y, Gupta P, Fenwick E, Man R, Wong CMJ, Tan ACS, Cheung CMG, Colega MT, Chong MF, Lai JS, Lamoureux EL. The Association of Dietary Patterns with Age-related Macular Degeneration in a Multi-ethnic Older Singaporean Population. Ophthalmologica. 2026 Jan 17:1-16.
9. Yee H, Wong CMJ, Gupta P, Thakur S, Fenwick E, Lamoureux EL, Man REK. Prevalence, Risk Determinants, and Burden of Undiagnosed Age-related Eye Diseases Among Older Asian Adults. JAMA Ophthalmol. 2026 Jan 1;144(1):23-32.
10. Soh ZD, Bai Y, Yu K, Zhou Y, Lei X, Thakur S, Lee Z, Phang LCL, Peng Q, Xue CC, Chong RS, Hoang QV, Raghavan L, Tham YC, Sabanayagam C, Wu WC, Ho MC, He J, Gupta P, Lamoureux EL, Saw SM, Nangia V, Panda-Jonas S, Xu J, Wang YX, Xu X, Jonas JB, Wong TY, Goh RSM, Liu Y, Cheng CY. An Integrated Language-vision Foundation Model for Conversational Diagnostics and Triaging in Primary Eye Care. Cell Rep Med. 2025 Dec 4:102476.
11. Yeo BSY, Song HJJMD, Tan BKJ, Suresh A, Ho OTW, Chan JH, Gao EY, Tan CJ, Teo CB, Chen CL, Tay L, Lamoureux EL, Hummel T, See A, Xu S, Toh ST, Charn TC, Teo NWY. Olfactory Impairment and Incident Cognitive Decline: A Systematic Review and Meta-analysis. Int Forum Allergy Rhinol. 2025 Dec;15(12):1347-1358.
12. Cheong KX, Chi M, Pan W, Lee YQ, Zhang Y, Hu Z, Htoon HM, Hoang QV, Chong MF, Lan W, Saw SM, Lamoureux EL. Diet and Myopic Macular Degeneration in the Aier-SERI High Myopia Adult Cohort Study. Acta Ophthalmol. 2025 Dec;103(8):891-899.
13. Matsumura S, Fenwick EK, Kawakami M, Takagi S, Lamoureux EL, Hori Y. Psychometric Evaluation of the Japanese Version of the Impact of Vision Impairment (IVI) Questionnaire using Rasch Analysis. Asia Pac J Ophthalmol (Phila). 2025 Nov-Dec;14(6):100204.
14. Jha D, Praveen AD, Baker A, Fung A, Cheong VS, Gupta P,Lamoureux EL, Hong N, Rhee Y, Koh VJW, Pálsson H, Taylor WR, Chan AW, Ferguson SJ, Helgason B. Dual-energy X-ray Absorptiometry Based Biofidelic Finite Element Models for Simulating Falls to the Hip: Impact of Trochanteric Soft Tissue Thickness on Fracture Risk. Clin Biomech (Bristol). 2025 Nov 21:106720.
15. Jha D, Chandran M, Koller D, Cheong VS, Praveen AD, Baker A, Gupta P, Lamoureux EL, Pálsson H, Ferguson SJ, Helgason B. Relationship Between Areal BMD, FRAX®, and Femoral Strength in Community-dwelling Older Asian Adults. Arch Osteoporos. 2025 Nov 4;20(1):139.
16. Pan W, Man REK, Fenwick EK, Hu Z, Jiang Y, Tan H, Chen Z, Hoang QV, Saw SM, Lamoureux EL, Lan W, Yang Z. A Psychometric Evaluation of the Chinese Impact of Vision Impairment (C-IVI) Questionnaire in an Adult Cohort with High Myopia using Rasch Analysis. PLoS One. 2025 Oct 9;20(10):e0327708.
17. Gao EY, Tan BKJ, Chan KL, Chia CXY, Tan CJ, Yeo BSY, Liu X, Tay L, Lamoureux EL, Teo NWY, Charn TC. Chronic Rhinosinusitis and Cognition: A Systematic Review and Meta-analysis. Rhinology. 2025 Oct 1;63(5):514-522.
18. Tham YC, Goh JHL, Nderitu P, Zhou Y, Ran AR, Srinivasan S, Yang GD, Kitema GF, Rawlinson P, Jiang H, Zou K, Cheung CY, Keane PA; Global RETFound Consortium. Building the World's First Truly Global Medical Foundation Model. Nat Med. 2025 Sep 8.
19. Man REK, Fenwick EK, Goh KJL, Teo PRT, Ang M, Hoang QV, Wong CW, Rosman M, Saw SM, Lamoureux EL. Psychometric Evaluation and Computerized Adaptive Testing Simulations of Myopic Refractive Intervention Quality of Life Item Banks. Transl Vis Sci Technol. 2025 Aug 1;14(8):4.
20. Cheong KX, Jiang Y, Htoon HM, Pan W, Foo LL, Hu Z, Chen L, Ang S, Lamoureux EL, Hoang QV, Saw SM, Lan W. Characteristics of Myopic Traction Maculopathy in the Aier-SERI High Myopia Adult Cohort Study. Ophthalmol Sci. 2025 Jul 24;5(6):100894.