Assoc Prof Damon Wong

​Assoc Prof Damon Wong is a Principal Investigator in the Ocular Imaging Department at the Singapore Eye Research Institute and holds a joint appointment as an Associate Professor with SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme (EYE ACP).

Assoc Prof Wong has been generally interested in exploring the use of computer vision, data science and artificial intelligence-driven techniques in healthcare with a focus in ophthalmology. He has been actively involved in developing approaches to better detect image-based biomarkers in major eye conditions including glaucoma, myopia and age-related macular degeneration.

Currently, his research revolves around the use of structural and vascular imaging for visual function modelling. He is also particularly interested in the application of AI-driven techniques to characterise vision-threatening conditions, enhance the prediction of progression detection from structural and functional modalities, and explore the use of synthetic data in ophthalmology.

• PhD (2007)
• BEng (2003)
  

• NMRC Clinician Innovator Award – Investigator (2026)
• IES Prestigious Engineering Achievement Award (2015)
• IES Prestigious Engineering Achievement Award (2013)
• A*STAR Graduate Scholarship (2003)

1. Kumar AJS, Chong RS, Crowston JG, Chua J, Bujor I, Husain R, Vithana EN, Girard MJA, Ting DSW, Cheng CY, Aung T, Popa-Cherecheanu A, Schmetterer L, Wong D. Evaluation of Generative Adversarial Networks for High-resolution Synthetic Image Generation of Circumpapillary Optical Coherence Tomography Images for Glaucoma. JAMA Ophthalmol. 2022. 140(10): p. 974-981. JIF 8.253.
2. Wong D, Chua J, Bujor I, Chong RS, Nongpiur ME, Vithana EN, Husain R, Aung T, Popa-Cherecheanu, A, Schmetterer L. Comparison of Machine Learning Approaches for Structure–function Modeling in Glaucoma. Ann N Y Acad Sci. 2022. 1515(1): p. 237-248. JIF 5.691.
3. Yow AP, Tan B, Chua J, Husain R, Schmetterer L, Wong D. Segregation of Neuronal-vascular Components in a Retinal Nerve Fiber Layer for Thickness Measurement using OCT and OCT Angiography. Biomed Opt Express. 2021. 12(6): p. 3228-3240. JIF 3.562.
4. Kallab M, Hommer N, Schlatter A, Chua J, Tan B, Schmidl D, Hirn C, Findl O, Schmetterer L, Garhöfer G, Wong D. Combining Vascular and Nerve Fiber Layer Thickness Measurements to Model Glaucomatous Focal Visual Field Loss. Ann N Y Acad Sci. 2022. 1511(1): p. 133-141. JIF 5.691.
5. Cahyo DA, Yow AP, Saw SM, Ang M, Girard M, Schmetterer L, Wong D. Multi-task Learning Approach for Volumetric Segmentation and Reconstruction in 3D OCT Images. Biomedical Optics Express. 2021. 12(12): p. 7348-7360. JIF 3.562.
6. Wong D, Chua J, Tan B, Yao X, Chong R, Sng CC, Husain R, Aung T, Garway-Heath D, Schmetterer L. Combining OCT and OCTA for Focal Structure–Function Modeling in Early Primary Open-angle Glaucoma. Invest Ophthalmol Vis Sci. 2021. 62(15): p. 8-8. JIF 4.925.
7. Wong D, Chua J, Baskaran M, Tan B, Yao X, Chan S, Tham YC, Chong R, Aung T, Lamoureux, EL. Factors Affecting the Diagnostic Performance of Circumpapillary Retinal Nerve Fibre Layer Measurement in Glaucoma. Br J Ophthalmol. 2021. 105(3): p. 397-402. JIF 5.907.
8. Calzetti G, Mursch-Edlmayr AS, Bata AM, Ungaro N, Mora P, Chua J, Schmidl D, Bolz M, Garhöfer G, Gandolfi S, Schmetterer L, Wong D. Measuring Optic Nerve Head Perfusion to Monitor Glaucoma: A Study on Structure-function Relationships using Laser Speckle Flowgraphy. Acta Ophthalmol. 2022. 100(1): p. e181-e191. JIF 3.988.
9. Wong D, Chua J, Lin E, Tan B, Yao X, Chong R, Sng C, Lau A, Husain R, Aung T, Schmetterer L. Focal Structure–Function Relationships in Primary Open-angle Glaucoma Using OCT and OCT-A Measurements. Invest Ophthalmol Vis Sci. 2020. 61(14): p. 33-33. JIF 4.925.
10. Yow AP, Lee WZ, Wong DWK, Tey HL, Subsurface Detection of Hair Follicles in Alopecia Areata using Optical Coherence Tomography. Skin Res Technol. 2022. JIF 2.24.
11. Chua J, Le TT, Sim YC, Chye HY, Tan B, Yao X, Wong D, Ang BW, Toh DF, Lim H. Relationship of Quantitative Retinal Capillary Network and Myocardial Remodeling in Systemic Hypertension. J Am Heart Assoc. 2022. 11(6): p. e024226. JIF 6.106.
12. Chua J, Li C, Ho LKH, Wong D, Tan B, Yao X, Gan A, Schwarzhans F, Garhöfer G, Sng CC. A Multi-regression Framework to Improve Diagnostic Ability of Optical Coherence Tomography Retinal Biomarkers to Discriminate Mild Cognitive Impairment and Alzheimer’s Disease. Alzheimers Res Ther. 2022. 14(1): p. 1-11. JIF 9.037.
13. Chua J, Bostan M, Li C, Sim YC, Bujor I, Wong D, Tan B, Yao X, Schwarzhans F, Garhöfer G. A Multi-Regression Approach to Improve Optical Coherence Tomography Diagnostic Accuracy in Multiple Sclerosis Patients without Previous Optic Neuritis. NeuroImage Clin. 2022. 34: p. 103010. JIF 4.891.
14. Kadziauskienė A, Chua J, Baskaran M, Yow AP, Tan B, Sng C, Ašoklis R, Lesinskas E, Crowston J, Schmetterer L, Wong DWK. Association Between Structure-function Characteristics and Visual Field Outcomes in Glaucoma Subjects with Intraocular Pressure Reduction after Trabeculectomy. J Glaucoma. 2020. 29(8): p. 648-655. JIF 2.503.
15. Fu H, Xu Y, Lin S, Wong DWK, Baskaran M, Mahesh M, Aung T, Liu J. Angle-closure Detection in Anterior Segment OCT Based on Multilevel Deep Network. IEEE Trans Cybern. 2019. 50(7): p. 3358-3366. JIF 19.118.
16. Yan Q, Xu M, Wong DWK, Taruya A, Tanaka A, Liu J, Wong P, Cheng J. Automatic Fibroatheroma Identification in Intravascular Optical Coherence Tomography Volumes. J Ambient Intell Humaniz Comput. 2019: p. 1-7. JIF 3.662.
17. Cheng J, Tao D, Quan Y, Wong DWK, Cheung GCM, Akiba M, Liu J. Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction. IEEE Trans Med Imaging. 2016. 35(10): p. 2270-2279. JIF 11.037.
18. Srivastava R, Yow AP, Cheng J, Wong DW, Tey HL. Three-dimensional Graph-based Skin Layer Segmentation in Optical Coherence Tomography Images for Roughness Estimation. Biomed Opt Express. 2018. 9(8): p. 3590-3606. JIF 3.562.
19. Cheng J, Liu J, Xu Y, Yin F, Wong DWK, Tan NM, Tao D, Cheng CY, Aung T, Wong TY. Superpixel Classification based Optic Disc and Optic Cup Segmentation for Glaucoma Screening. IEEE Trans Med Imaging. 2013. 32(6): p. 1019-1032. JIF 11.037.
20. Trucco E, Ruggeri A, Karnowski T, Giancardo L, Chaum E, Hubschman JP, Al-Diri B, Cheung CY, Wong D, Abràmoff M, Lim G, Kumar D, Burlina P, Bressler NM, Jelinek HF, Meriaudeau F, Quellec G, Macgillivray T, Dhillon B. Validating Retinal Fundus Image Analysis Algorithms: Issues and a Proposal. Invest Ophthalmol Vis Sci. 2013. 54(5): p. 3546-3559. JIF 4.925.