Prof Wong Tien Yin

Professor Tien Yin Wong is a physician-scientist-innovator and was previously Arthur Lim Professor and Medical Director of the Singapore National Eye Centre (2014-2021), and prior to that, Executive Director of the Singapore Eye Research Institute (2009-2013). He is currently based in Beijing, China at Tsinghua University as the founding head and Senior Vice-Chancellor of Tsinghua Medicine.

Prof Wong is a practicing retinal specialist, with a research portfolio on retinal diseases, ocular imaging, AI and digital technology. He has published >1,700 peer-reviewed papers (H-index >240, highly cited researcher 2020-2025), given >600 invited named, plenary and symposium lectures, and received >US$100 million in grant funding. Prof Wong has been recognised with multiple international awards, including Arnall Patz Medal (Macula Society), Jose Rizal Medal (Asia Pacific Academy of Ophthalmology) and Friedenwald Award (ARVO). He has received Singapore’s President’s Science Award and the President’s Technology Award in 2010 and 2014 respectively. He is an elected Member/Fellow of five national academies: the US National Academy of Medicine, the UK Royal Society, the Singapore National Academy of Science, the Australian Academy of Health and Medical Sciences and the US National Academy of Inventors.

• FRCOphth (2019)    
  
• FAMS (2010)
• FRANZCO (2004)
  
• PhD (Johns Hopkins) (2002)
  
• M Med(Ophth) (1999)
  
• FRCSE (1999) 
  
• MPH (Johns Hopkins) (1997) 
  
• MBBS (1992) 
  

• President, Asia Pacific Vitreo-retinal Society (2026 – Present)
• Advisor, Global Ophthalmic AI and Technology Society (GOATS), Hong Kong (2026 – Present)
• Vice President, Association for Research and Vision in Ophthalmology, USA (2025 – Present)
• Founding Academician, Academia Retina Internationalis (ARI) (2025 – Present)
• Academic Advisory Committee, (International Division), Chinese Academy of Medical Sciences (CAMS) (2024 – Present)
• Senior Advisor, SingHealth Board of Advisors (2022 – Present)
• Founding Member, Future Vision Forum, USA (2021 – Present)
• Advisory Board Member, Saudi NIH (2021 – Present)
• Scientific Advisory Board Member, ALDROPIKA Therapeutics (2021 – Present)
• Director, Ophthalmology Foundation Board (2021 – 2025)
• Assistant Master (Academic Affairs), Academy of Medicine, Singapore (2020 – 2023)
• Vice Chairman, Deanery Academic Board, Academy of Medicine, Singapore (2020 – 2022)
• Chairman, Singapore Biodesign Steering Committee (2019 – Present)
• President, Asia-Pacific Ocular Imaging Society (2018 – Present)
• Deputy Group CEO, Research & Education, Singapore Health Services, Singapore (2018 – 2021)
• Vice President, Asia Pacific Vitreo-retinal Society (2017 – 2021)
• Council Member, Asia Pacific Tele-ophthalmology Society (2016 – 2021)
• Council Member, College of Ophthalmologists, Singapore (2016 – 2021)
• Council Member, Academy of Medicine Singapore (2015 – 2023)
• Vice-Dean, Duke-NUS Medical School, National University of Singapore, Singapore (2014 – 2021)
• Chair & Medical Director, Singapore National Eye Centre (2014 – 2021)
• Chairman, Board of Directors, Singapore Eye Research Institute (2014 – 2021)
• Council Member, Asia Pacific Academy of Ophthalmology (2010 - Present)
• Board Member, National Medical Research Council, Singapore (2009 - Present)

• Elected Fellow, National Academy of Inventors, USA (2025)
• Elected Fellow, Royal Society, United Kingdom (2025)
• Changjiang (Yangtze River) Scholar, Ministry of Education, China (2024)
• The Beijing Great Wall Friendship Award, People's Government of Beijing Municipality, China (2024)
• College of Clinician Scientists Medal, College of Clinician Scientist, Academy of Medicine, Singapore (2023)
• Friedenwald Award, Association for Research in Vision and Ophthalmology (ARVO), USA (2023)
• Elected Fellow (Corresponding), Australian Academy of Health and Medical Sciences, Australia (2021)
• IAPB Vision Excellence Award, International Agency for the Prevention of Blindness (2020)
• Elected Member (International), US National Academy of Medicine (2020)
• Jose Rizal Medal Medal, Asia-Pacific Academy of Ophthalmology (APAO) (2019)
• Elected Fellow, Singapore National Academy of Science, Singapore (2018)
• Sir Runme Shaw Memorial Lecture, Academy of Medicine Singapore (2017)
• Senior Achievement Award, American Academy of Ophthalmology (AAO) (2016)
• Tano Lecture, Asia Pacific Vitreo-Retina Society (2015)
• President's Science and Technology Award, Singapore (2014)
• Arnall Patz Medal, Macula Society, USA (2014)
• Singapore Translational Research (STaR) Award, National Medical Research Council (2014)
• Eisenhower Fellowship, USA (2013)
• Johns Hopkins Bloomberg School of Public Health Knowledge of the World Award, USA (2011)
• Elected Member, Academia Ophthalmologic Internationalis (AOI) (2010)
• Fred Hollows Lecture, Australian Ophthalmic and Visual Sciences Meeting, Australia (2010)
• President’s Science Award, Singapore (2010)
• Outstanding Researcher of the Year, National University of Singapore, Singapore (2009)
• The Australian Society for Medical Research AMGEN Medical Researcher Award, Australia (2007)
• The Alcon Research Institute Award, USA (2006)
• The Commonwealth Minister of Health Award for Excellence in Medical Research, Australia (2006)
• The Woodward Medal for Science and Technology, University of Melbourne, Australia (2005)

• Artificial Intelligence and Large Language Models
• Global Epidemiology of Eye Diseases
• Retinal Vascular Imaging and Oculomics
• Diabetic Retinopathy Screening and Diagnosis
• Clinical Trials and Implementation Studies

1. Wu Y, Qian B, ... Wong TY, Sheng B. An Eyecare Foundation Model for Clinical Assistance: A Randomized Controlled Trial. Nature Medicine 2025 Oct;31(10):3404-3413.
2. Zeng D, Qin Y, Sheng B, Wong TY. DeepSeek's "Low-Cost" Adoption Across China's Hospital Systems: Too Fast, Too Soon?. JAMA. 2025 Jun 3;333(21):1866-1869.
3. Lanzetta P, Korobelnik JF, ... Wong TY; PULSAR Investigators. Intravitreal Aflibercept 8 Mg in Neovascular Age-related Macular Degeneration (PULSAR): 48-week Results from a Randomised, Double-masked, Non-inferiority, Phase 3 Trial. Lancet. 2024 Mar 23;403(10432):1141-1152.
4. Dai L, Sheng B, ... Wong TY, Jia W. A Deep Learning System for Predicting Time to Progression of Diabetic Retinopathy. Nature Medicine. 2024 Feb;30(2):584-594.
5. Heier JS, Khanani AM, ... Wong TY; TENAYA and LUCERNE Investigators. Efficacy, Durability, and Safety of Intravitreal Faricimab Up to Every 16 weeks for Neovascular Age-related Macular Degeneration (TENAYA and LUCERNE): Two Randomised, Double-masked, Phase 3, Non-inferiority Trials. Lancet. 2022 Feb 9;399(10326):729-740.
6. Cheung CY, Xu D, Cheng CY, ... Wong TY. A Deep-learning System for the Assessment of Cardiovascular Disease Risk via the Measurement of Retinal-vessel Calibre. Nature Biomedical Engineering 2021 Jun;5(6):498-508.
7. Sabanayagam C, Xu D, ... Wong TY. A Deep Learning Algorithm to Detect Chronic Kidney Disease from Retinal Photographs in Community-based Populations. Lancet Digital Health. 2020 Jun;2(6):e295-e302.
8. Ting DSW, Carin L, Dzau V, Wong TY. Digital Technology and COVID-19. Nature Medicine 2020;26(4):459-461.
9. Milea D, Najjar RP, Zhubo J,  ... Wong TY, Biousse V; BONSAI Group. Artificial intelligence to Detect Papilledema from Ocular Fundus Photographs. New England Journal of Medicine 2020;382:1687-1695.
10. Ting DSW, Cheung CY,  ... Wong TY. Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye using Retinal Images from Multi-ethnic Populations with Diabetes. JAMA. 2017;318(22):2211-2223.
11. Wong TY, Bressler NM. Artificial Intelligence with Deep Learning Technology Looks into Diabetic Retinopathy Screening. JAMA. 2016;316(22):2366-2367.
12. Wong TY, Cheung CM, Larsen M, Sharma S, Simó R. Diabetic Retinopathy. Nature Reviews Disease Primers 2016;2:16012.
13. Lim L, Mitchell P, Seddon J, Holz F, Wong TY. Age-related Macular Degeneration. Lancet 2012. 379(9827): p. 1728-1738.
14. Wong TY, Scott IU. Retinal Vein Occlusion. New England Journal of Medicine 2010; 363(22): 2135-44.
15. Wong TY, Liew G, Tapp R, et al. Relation of Fasting Glucose and Retinopathy for Diagnosis of Diabetes: Three Population-based Cross-sectional Studies. Lancet 2008; 371: 736-743.
16. Mohamed Q, Gillies, MC, Wong TY. Management of Diabetic Retinopathy: A Systematic Review. JAMA. 2007;298:902-916.
17. Wong TY, Rosamond WR, Chang P, et al. Retinopathy and Risk of Congestive Heart Failure. JAMA. 2005: 293:63-69.
18. Wong TY, Mitchell P. Hypertensive Retinopathy. New England Journal of Medicine. 2004;351:2310-7.
19. Wong TY, Klein R, Sharrett AR, et al. Retinal Arteriolar Narrowing and Risk of Diabetes in Middle-aged Persons. JAMA. 2002; 287: 2528-33.
20. Wong TY, Klein R, Couper DJ, et al. Retinal Microvascular Abnormalities and Incident Clinical Strokes. The Atherosclerosis Risk in the Communities Study. Lancet. 2001: 358: 1134-40.