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Dr Beau Fenner

Dr Fenner Beau

MD, M Med(Ophth), FRCOphth, FAMS

Consultant

Singapore National Eye Centre

Specialty: Medical Retina

Sub-specialties: Medical Retina

Clinical Appointments

  • Consultant Medical Retina Department Singapore National Eye CentreSingapore National Eye Centre

Profile

Beau Fenner, MD, PhD, is a Consultant Ophthalmologist in the Department of Medical Retina at the Singapore National Eye Centre. He completed undergraduate and PhD studies in Molecular Biology in Western Australia prior to undertaking postdoctoral research at the National University of Singapore and the Royal College of Surgeons in Dublin. He completed his MD studies at Duke-NUS Graduate Medical School and Ophthalmology residency at the Singapore National Eye Centre, after which he undertook clinical fellowship training in Medical Retina at the Singapore National Eye Centre and additional subspecialty training in Inherited Retinal Diseases at the University of Iowa. In addition to his clinical work, he is actively engaged in clinical and translational research of Inherited Retinal Diseases, Age-Related Macular Degeneration, Diabetic Retinopathy, and Retinal Imaging.

Dr Fenner is the Principal Investigator of the Southeast Asian Database for Inherited Retinal Diseases, Singapore’s largest prospective study of Inherited Retinal Disease patients. He is also the Principal Investigator for numerous ongoing studies relating to Inherited Retinal Disease diagnosis and therapeutics, as well as projects relating to AMD in Asian patients.

Dr Fenner has received a number of prestigious awards, including the Innovation Research Australia Award, Singapore Millennium Foundation Award, Duke-NUS Dean’s Scholarship Award, Richard Fan Outstanding Ophthalmology Resident Award, American Academy of Ophthalmology International Education Award, and the Mina Chung Inherited Retinal Disease Fellowship Award.

Education

  • FRCOphth (2020)
  • FAMS (2020)
  • M Med(Ophth) (2018)
  • MD (2014)
  • PhD (2004)
  • BSc 1st Hons (1999)

Professional Appointments and Committee Memberships

  • Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore (2023 to present)
  • Member, Association for Vision Research and Ophthalmology (2022 to present)
  • Member, International Society for Genetic Eye Diseases and Retinoblastoma (2021 to present)
  • Clinical Assistant Professor, SingHealth Duke-NUS Ophthalmology and Visual Sciences Academic Clinical Programme (2021 to present)
  • Fellow, Academy of Medicine in Singapore (2021 to present)
  • Fellow, Royal College of Ophthalmologists (2020 to present)
  • Member, American Academy of Ophthalmology (2019 to present)
  • Member, European Society of Retina Specialists (2019 to present)
  • Member, Singapore Society of Ophthalmologists (2018 to present)

Awards

Research Interests

  • Diagnosis, genetics, and gene- and cell-based therapeutics for Inherited Retinal Diseases (IRDs)
  • Multimodal imaging for Age-related Macular Degeneration (AMD) and Diabetic Retinopathy

Publications

  1. Chan, C.M., T.E. Tan, K. Jain, Y. Bylstra, R.S. Mathur, R.W.C. Tang, B.J.H. Lee, S.S. Jamuar, S. Kam, E.N. Vithana, W.K. Lim, and B.J. Fenner, Retinitis pigmentosa associated with the EYS C2139Y variant: an important cause of blindness in East Asian populations. Retina, 2023. In Press.

  2. Fenner, B.J., J.F. Russell, A.V. Drack, A.V. Dumitrescu, E.H. Sohn, S.R. Russell, H.C. Boldt, L.M. Affatigato, J.M. Hoffmann, J.L. Andorf, E.M. Stone, and I.C. Han, Long-term functional and structural outcomes in X-linked retinoschisis: implications for clinical trials. Front Med (Lausanne), 2023. 10: p. 1204095.

  3. Chay, J., R.W.C. Tang, T.E. Tan, C.M. Chan, R. Mathur, B.J.H. Lee, H.H. Chan, S. Sim, S. Farooqui, K.Y.C. Teo, E.K. Fenwick, E.L. Lamoureux, C.M.G. Cheung, and B.J. Fenner, The economic burden of inherited retinal disease in Singapore: a prevalence-based cost-of-illness study. Eye (Lond), 2023.

  4. Tan, A.C., M.L. Chee, B.J. Fenner, P. Mitchell, Y.C. Tham, T. Rim, K. Teo, S.S. Sim, C.Y. Cheng, T.Y. Wong, U. Chakravarthy, and C.M.G. Cheung, Six-year incidence of age-related macular degeneration and correlation to OCT-derived drusen volume measurements in a Chinese population. Br J Ophthalmol, 2023. 107(3): p. 392-398.

  5. Takahashi, K., Y. Song, K.X. Cheong, B.J. Fenner, K.Y.C. Teo, M.L. Chee, H. Li, Y.C. Tham, C.M.G. Cheung, C.Y. Cheng, T.Y. Wong, Y. Yanagi, and A.C.S. Tan, Pattern and Characteristics of Drusen Subtypes in Chinese and Indian Populations in Singapore. Retina, 2023. 43(2): p. 303-312.

  6. Lee, B.J.H., Y.C. Tham, T.E. Tan, Y. Bylstra, W.K. Lim, K. Jain, C.M. Chan, R. Mathur, C.M.G. Cheung, and B.J. Fenner, Characterizing the genotypic spectrum of retinitis pigmentosa in East Asian populations: a systematic review. Ophthalmic Genet, 2023. 44(2): p. 109-118.

  7. Fenner, B.J., H. Li, A.T.L. Gan, Y.S. Song, Y.C. Tham, J.B. Jonas, Y.X. Wang, C.Y. Cheng, T.Y. Wong, K.Y.C. Teo, A.C.S. Tan, Q. Fan, and C.M.G. Cheung, Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness. Invest Ophthalmol Vis Sci, 2023. 64(2): p. 10.

  8. Vyas, C.H., C.M.G. Cheung, J.M.N. Jordan-Yu, H. Shimizu, A.C.S. Tan, S.S. Sim, B.J. Fenner, M. Akiba, U. Chakravarthy, and K.Y.C. Teo, Novel volumetric imaging biomarkers for assessing disease activity in eyes with PCV. Sci Rep, 2022. 12(1): p. 2993.

  9. Sia, J.T., E.P.X. Lee, C.M.G. Cheung, E.K. Fenwick, A. Laude, K.C. Ho, B.J. Fenner, T.Y. Wong, D. Milea, E.L. Lamoureux, R.E.K. Man, and R.P. Najjar, Associations between age-related macular degeneration and sleep dysfunction: A systematic review. Clin Exp Ophthalmol, 2022. 50(9): p. 1025-1037.

  10. Lim, H.B., T.E. Tan, B.J. Fenner, J. Heah, A. Arundhati, W.B. Khor, P.Y. Boey, S.Y. Lee, E.Y.M. Wong, and T.Y. Wong, Clinical operational considerations and responses to lockdown and reopening in the Covid-19 pandemic: experience of a tertiary ophthalmology centre in Singapore. Eye (Lond), 2022. 36(10): p. 1924-1933.

  11. Fenner, B.J., K.Y.C. Teo, Y.C. Tham, U. Chakravarthy, and C.M.G. Cheung, Prevalence of Polypoidal Choroidal Vasculopathy Using Non-indocyanine green angiography-based Criteria. Ophthalmol Retina, 2022. 6(2): p. 179-181.

  12. Fenner, B.J., C.M.G. Cheung, S.S. Sim, W.K. Lee, G. Staurenghi, T.Y.Y. Lai, P. Ruamviboonsuk, G. Kokame, Y. Yanagi, and K.Y.C. Teo, Evolving treatment paradigms for PCV. Eye (Lond), 2022. 36(2): p. 257-265.

  13. Chay, J., B.J. Fenner, E.A. Finkelstein, K.Y.C. Teo, and C.M.G. Cheung, Real-world cost-effectiveness of anti-VEGF monotherapy and combination therapy for the treatment of polypoidal choroidal vasculopathy. Eye (Lond), 2022. 36(12): p. 2265-2270.

  14. Vyas, C.H., C.M.G. Cheung, C. Tan, C. Chee, K. Wong, J.M.N. Jordan-Yu, T.Y. Wong, A. Tan, B. Fenner, S. Sim, and K.Y.C. Teo, Multicentre, randomised clinical trial comparing intravitreal aflibercept monotherapy versus aflibercept combined with reduced-fluence photodynamic therapy (RF-PDT) for the treatment of polypoidal choroidal vasculopathy. BMJ Open, 2021. 11(7): p. e050252.

  15. Tan, T.E., B.J. Fenner, V.A. Barathi, S.B.B. Tun, Y.S. Wey, A.S.H. Tsai, X. Su, S.Y. Lee, C.M.G. Cheung, T.Y. Wong, J.S. Mehta, and K.Y.C. Teo, Gene-Based Therapeutics for Acquired Retinal Disease: Opportunities and Progress. Front Genet, 2021. 12: p. 795010.

  16. Tan, A.C., M.L. Chee, B.J. Fenner, P. Mitchell, Y.C. Tham, T. Rim, K. Teo, S.S. Sim, C.Y. Cheng, T.Y. Wong, U. Chakravarthy, and C.M.G. Cheung, Six-year incidence of age-related macular degeneration and correlation to OCT-derived drusen volume measurements in a Chinese population. Br J Ophthalmol, 2021.

  17. Song, Y., Y.C. Tham, C. Chong, R. Ong, B.J. Fenner, K.X. Cheong, K. Takahashi, J.M. Jordan-Yu, K.Y.C. Teo, A.C.S. Tan, C.Y. Cheng, T.Y. Wong, U. Chakravarthy, Y. Yanagi, and G.C.M. Cheung, Patterns and Determinants of Choroidal Thickness in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study. Ophthalmol Retina, 2021. 5(5): p. 458-467.

  18. Lim, H.B., T.E. Tan, B.J. Fenner, J. Heah, A. Arundhati, W.B. Khor, P.Y. Boey, S.Y. Lee, E.Y.M. Wong, and T.Y. Wong, Clinical operational considerations and responses to lockdown and reopening in the Covid-19 pandemic: experience of a tertiary ophthalmology centre in Singapore. Eye (Lond), 2021.

  19. Fenner, B.J., K.Y.C. Teo, Y.C. Tham, U. Chakravarthy, and C.M. Gemmy Cheung, Prevalence of polypoidal choroidal vasculopathy using non-ICGA based criteria. Ophthalmol Retina, 2021.

  20. Fenner, B.J., T.E. Tan, A.V. Barathi, S.B.B. Tun, S.W. Yeo, A.S.H. Tsai, S.Y. Lee, C.M.G. Cheung, C.M. Chan, J.S. Mehta, and K.Y.C. Teo, Gene-Based Therapeutics for Inherited Retinal Diseases. Front Genet, 2021. 12: p. 794805.

Research Trials