Clin Assoc Prof Andrew Tsai

Dr Andrew Tsai is an adult and pediatric retinal specialist, Senior Consultant in the Surgical Retina Department at the Singapore National Eye Centre (SNEC) and Clinical Associate Professor with the SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme. He is the Program Director of Fellowships and Director of Operating Theatre and Inpatient Services, SNEC.

Dr Tsai graduated from the Yong Loo Lin School of Medicine, National University of Singapore (NUS) with a Bachelor of Medicine and Bachelor or Surgery (MBBS) degree in 2008. He completed his Master of Medicine in Ophthalmology in 2014 and became Fellow of the Royal College of Ophthalmologists in 2015. He gained accreditation as a specialist in Ophthalmology in 2016 and became a Fellow of the Academy of Medicine, Singapore in the same year. He subsequently completed advanced subspecialty training in Medical and Surgical Retina in 2019. He underwent further training in advanced vitreoretinal surgery and pediatric retinal diseases at Illinois Eye and Ear Infirmary, University of Illinois Chicago and Chang Gung Memorial Hospital, Taoyuan Taiwan. Dr Tsai also holds a Master of Clinical Investigation from NUS.

Dr Tsai believes in an evidence-based and patient-centric approach to clinical care. His current clinical practice includes adult and pediatric vitreoretinal surgery, medical retina, general cataract and comprehensive ophthalmology.

• Asia-Pacific Pediatric Retina Association (2024)
• Retina Society (2024)
• Vit-Buckle Society (2022)
• SNEC Strategy & Innovation Transformation Committee (2024)
• SNEC OT Committee (2022)
• Member, SNEC Fellowship Coordination Committee (2021)

• Star Award, Singapore Health Quality Service Awards, SingHealth (2025)
• Distinguished Contributor Award, Journal of Vitreoretinal Diseases (2023)
• COVID-19 Resilience Medal (2023)
• The Commendation Medal Pingat Kepujian (COVID-19), National Awards (2023)
• Best Research by Fellow, CGMH Resident/Fellow Research Day (2022)
• Gold Award, Singapore Health Quality Service Awards, SingHealth (2022)
• Long Service Award (5 years), Singapore National Eye Centre (2021)
• Hero Award, Singapore Health Quality Service Awards, SingHealth (2021)
• Silver Award, Singapore Health Quality Service Awards, SingHealth (2020)
• 10 year Long Service Award, SingHealth (2020)
• AM.EI Golden Apple Award 2019
• MOH Healthcare Research Scholarship, Master of Clinical Investigation Program (2017)
• Outstanding Resident Award,  SingHealth Excels (RiSE) Awards (2016)
• Richard Fan Gold Medal Award for Outstanding Senior Resident, Singapore National Eye Centre (2015)
• Junior Doctor Teaching Award, Yong Loo Lin School of Medicine, National University of Singapore (2015)
• Master of Medicine Gold Medal (NUS) for Best Candidate in M Med Ophthalmology (2014)
• Outstanding Performance for Intermediate/In-Training Examination, SingHealth Excels (RiSE) Awards (2014)
• Best Resident, SingHealth Best Junior Doctor Award 2013
• Outstanding Resident, SingHealth Excels (RiSE) Awards (2012 – 2013)
• Training Award, Ministry of Health (2013 – 2016)
• Appreciation Award, Singapore National Eye Centre (2011)
• Chief of Defence Force Essay Competition Merit Award (2010 / 2011)

1. Persistent avascular retina in retinopathy of prematurity.
   Tan TF, Tay SA, Agarwal-Sinha S, Tan GSW, Wu WC, Tsai ASH.
   Graefes Arch Clin Exp Ophthalmol. 2025 Apr 3. doi: 10.1007/s00417-025-06820-x. Epub ahead of print. PMID: 40178600.
   
   
2. Clinical Characteristics and Treatment Outcomes in Unilateral Coats disease – a Global Collaborative Study.
   Tsai ASH, Wang CT, Lee TC, Nagiel A, Matsunaga K, Harper CA 3rd, Wood EH, Kim SJ, Hwang S, Shapiro MJ, Blair MP, Toth CA, Valikodath N, Martinez-Castellanos MA, Trese MGJ, Capone A Jr, Drenser K, Tauqeer Z, Besirli CG, Eton E, Hartnett ME, Bair C, Kennedy B, Kusaka S, Mano F, Chang EY, Rao P, Hunt PJ, Walsh MK, Moore S, Sears JE, Abraham J, Schulgit M, Vagaggini T, Quiram PA, Vavvas D, Patel NA, Hoyek S, Chan RVP, Challa N, Mendel T, Dewan KS, Rogers DL, Amphornphruet A, Wu WC..
   Ophthalmol Retina. 2024 Nov 27:S2468-6530(24)00574-8. doi: 10.1016/j.oret.2024.11.017. Epub ahead of print. PMID: 39613161.
   
   
3. Implementation of Artificial Intelligence in Retinopathy of Prematurity Care: Challenges and Opportunities.
   Tsai ASH, Yip M, Song A, Tan GSW, Ting DSW, Campbell JP, Coyner A, Chan RVP.
   Int Ophthalmol Clin. 2024 Oct 1;64(4):9-14. doi: 10.1097/IIO.0000000000000532. Epub 2024 Oct 29. PMID: 39480203.
   
   
4. Reshaping vitreoretinal surgery: Intraoperative optical coherence tomography as a tool for enhancing surgical decision making in complex cases. Chang YH, Chou HD, Tan GSW, Tsai ASH.
   TJO – in press
   
   
5. Cataract Surgery and Cognitive Benefits in The Older Persons – A systematic review and Meta-analysis.
   Yeo BSY, Ong R, Ganasekar P, Tan BKJ, Seow DCC, Tsai ASH (corresponding).
   Ophthalmology 2024 – Aug;131(8):975-984. doi: 10.1016/j.ophtha.2024.02.003.
   
   
6. Artificial Intelligence, Digital Imaging and Robotics Technologies for Surgical Vitreoretinal Diseases.
   Poh SS, Sia JT, Yip MY, Tsai AS, Lee SY, Tan GS, Weng CY, Kadonoso K, Kim M, Yonekawa Y, Ho AC, Toth CA, Ting DS.
   Ophthalmol Retina. 2024 Jan 25:S2468-6530(24)00044-7. doi: 10.1016/j.oret.2024.01.018. Epub ahead of print. PMID: 38280425.
   
   
7. Serial OCT Imaging of Spontaneous Closure of a Pediatric Traumatic Macular Hole.
   Tsai ASH, Kaufman AR, Chan RVP.
   J Vitreoretin Dis. 2024 Sep 19:24741264241275275. doi: 10.1177/24741264241275275. Epub ahead of print. PMID: 39539822; PMCID: PMC11556303.
   
   
8. Aggressive onset and progressive FEVR phenotype in a child with novel mutations in LRP5 and TSPAN12.
   Tsai ASH, Chan RVP, Blair MP, Shapiro MJ.
   Journal of VitreoRetinal Diseases 2024 doi:10.1177/24741264241246864
   
   
9. Long term clinical outcomes and genotype-phenotype correlation in Familial Exudative Vitreoretinopathy in a tertiary referral center.
   Tsai ASH, Kang EYC, Wang NK, Lee H, Seo GH, Khang R, Wu, WC.
   RETINA 2023 Jun 16. doi: 10.1097/IAE.0000000000003868. Epub ahead of print. PMID: 37339455
   
   
10. Efficacy of Smartphone-Based Telescreening for Retinopathy of Prematurity With and Without Artificial Intelligence in India.
    Young BK, Cole ED, Shah PK, Ostmo S, Subramaniam P, Venkatapathy N, Tsai ASH, Coyner AS, Gupta A, Singh P, Chiang MF, Kalpathy-Cramer J, Chan RVP, Campbell JP.
    JAMA Ophthalmol. 2023 May 11. doi: 10.1001/jamaophthalmol.2023.1466. PMID: 37166816
    
    
11. Optical Coherence Tomography and Optical Coherence Tomography Angiography in Pediatric Retinal Diseases.
    Wang CT, Chang YH, Tan GSW, Lee SY, Chan RVP, Wu WC, Tsai ASH.
    Diagnostics. 2023; 13(8):1461.
    
    
12. Survey of Ophthalmology Training Experiences Amongst Young Ophthalmologists in the Asia-Pacific.
    Tsai ASH, Yeo BSY… Ang M.
    Asia Pacific Journal of Ophthalmology 2022 - doi: 10.1097/APO.0000000000000556. Epub ahead of print. PMID: 36102646.
    
    
13. Current Management of Retinopathy of Prematurity.
    Tsai ASH, Acaba-Berrocal L, Sobhy M, Cole E, Ostmo S, Jonas K, Campbell JP, Chiang MF, Chan RVP.
    Current Treatment Options in Pediatrics 2022 – 8, 246–261 (2022). https://doi.org/10.1007/s40746-022-00249-8
    
    
14. Assessment and Management of Retinopathy of Prematurity in the Era of Anti-Vascular Endothelial Growth Factor (VEGF).
    Tsai ASH, Chou HD, Ling XC, Al-Khaled T, Valikodath N, Cole E, Yap VL, Chiang MF, Chan RVP, Wu WC
    [published online ahead of print, 2021 Nov 9]. Prog Retin Eye Res. 2021;101018. doi:10.1016/j.preteyeres.2021.101018
    
    
15. Diabetic Macular Ischemia: Influence of Optical Coherence Tomography Angiography Parameters on Changes in Functional Outcomes over 1-Year
    Tsai ASH, Jordan-Yu J, ATL Gan.. Cheung CMG
    Investigative Ophthalmology & Visual Science 2021 Jan 4;62(1):9
    
    
16. Digital Screen Time During COVID-19 Pandemic – Risk for a Further Myopia Boom?
    Wong CW, Tsai A, Jonas JB, Ohno-Matsui K, Chen J, Ang M, Ting DS
    American Journal of Ophthalmology 2020 Jul 29:S0002-9394(20)30392-5. doi: 10.1016/j.ajo.2020.07.034
    
    
17. 25-years Trends and Risk factors of Surgical Outcomes of Giant Retinal Tear- Rhegmatogenous Retinal Detachments
    Ting DS, Foo V, Tan TE…Tsai A...Shu Yen Lee
    Sci Rep. 2020 Mar 25;10(1):5474
    
    
18. DIABETIC MACULAR ISCHEMIA: Correlation of retinal vasculature changes by optical coherence tomography angiography and functional deficit
    Tsai A, Gan ATL, Ting DS, Wong CW…Cheung CMG
    Retina 2020 Nov;40(11):2184-2190
    
    
19. PEDIATRIC RETINAL DETACHMENT IN AN ASIAN POPULATION WITH HIGHPREVALENCE OF MYOPIA - Clinical Characteristics, Surgical Outcomes, and Prognostic Factors
    Tsai A, Wong CW, Lim LS, Yeo I, Wong D, Wong E, Ang CL, Ong SG, Lee SY, Tan G
    Retina 2018 Jul 13
    
    
20. Retinal Angiomatous Proliferation
    Tsai AS, Cheung N, Gan AT, Jaffe GJ, Sivaprasad S, Wong TY, Cheung CM
    Survey of Ophthalmology 2017 Feb 8 PMID:28189495
    
    
21. Prognostic Factor Analysis of Vitrectomy for Retinal Detachment Associated with Myopic Macular Holes
    Lim LS, Tsai A, Wong D, Wong E, Yeo I, Loh BK, Ang CL, Ong SG, Lee SY
    Ophthalmology 2014 Jan;121(1):305-10