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Dr Tan Tien-En

Dr Tan Tien-En

MBBS(Hons), M Med(Ophth), FRCOphth, FAMS

Associate Consultant

Singapore National Eye Centre

Specialty: Cataract & Comprehensive Ophthalmology, Ophthalmology

Sub-specialties: Cataract & Comprehensive Ophthalmology

Clinical Appointments

  • Associate Consultant Cataract & Comprehensive Ophthalmology Department Singapore National Eye CentreSingapore National Eye Centre

Academic Appointments

  • Clinical Asst Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


Dr Tan Tien-En is an Associate Consultant with the Cataract & Comprehensive Ophthalmology Department at the Singapore National Eye Centre, and is also a sub-specialty fellow with the Medical Retina and Surgical Retina Departments, under the Advanced Clinical Specialist Program. His current practice includes the management of cataracts, and retinal conditions such as age-related macular degeneration and diabetic retinopathy.

Dr Tan completed his medical training at the Yong Loo Lin School of Medicine, National University of Singapore in 2014, and graduated as a top student, with an MBBS (Honours). He was the recipient of many awards for academic excellence, including the Gold Medal and Book Prize in Ophthalmology, the S.S. Ratnam Book Prize, the Nihal Kaur Memorial Medal, the Nihal Kaur Sidhu Medal in Obstetrics and Gynaecology, the Singapore Medical Association Bronze Medal, and the Yeo Khuan Joo Gold Medal. Dr Tan completed his specialist training in Ophthalmology at the Singapore National Eye Centre in 2022. During his training he was recognized with the Outstanding Resident Award three times, was conferred the Richard Fan Gold Medal Award, and served as Chief Resident of the Ophthalmology Residency Programme. He was inducted as a Fellow of the Royal College of Ophthalmologists (FRCOphth), and was conferred a Master of Medicine in Ophthalmology, M Med(Ophth), and the Master of Medicine (Ophthalmology) Medal in 2020. Dr Tan completed the Ophthalmology Exit Examination in 2022, where he was a double Gold medallist.

Dr Tan firmly believes in the importance of research, and relying on scientific evidence to provide the best care for his patients. His research interests include developing gene-based and other novel therapies for blinding inherited and age-related retinal diseases, diabetic retinopathy, and artificial intelligence, and he has published scientific papers in respected journals in these areas. Dr Tan has also been invited to speak at international scientific meetings, where he has been awarded for his research work and presentations. He was inducted into the Khoo Scholars’ Programme by Duke-NUS Medical School in 2020, and is an Adjunct Research Fellow with the Ophthalmology & Visual Sciences Academic Clinical Programme (EYE ACP) in Duke-NUS Medical School.

Dr Tan also believes in mentoring and educating the next generation, and is a keen clinical educator who has been recognized for his dedication with awards such as the Inspiring Resident Educator Award in 2020 and 2022, the SNEC-SERI Young Educator Award (Senior Resident) in 2021, and the SNEC-SERI Outstanding Educator Award in 2022. Dr Tan was appointed as a SingHealth Associate in Education in 2022.


  • FAMS (2022)
  • ​FRCOphth (2020)
  • M Med(Ophth) (2020)
  • MBBS(Hons) (2014)

Professional Appointments and Committee Memberships

  • ​Fellow, The Royal College of Ophthalmologists (RCOphth), United Kingdom (2020 – present)
  • Fellow, Academy of Medicine, Singapore (2022 – present)
  • Member, European Society of Retina Specialists (EURETINA) (2020 – present)
  • Member, Singapore Society of Ophthalmology (2020 – present)
  • Member, Asia-Pacific Academy of Ophthalmology (APAO) (2019 – present)
  • Member, The Association for Research in Vision and Ophthalmology (2018 – 2019)
  • Honorary Committee Member, SingHealth Cluster Artificial Intelligence (AI) Program (2021 – present)
  • Member, Secretariat, Singapore National Eye Centre Global Ophthalmology Unit (2020 – present)
  • Executive Secretariat, Forward Planning Covid-19 Committee, Singapore National Eye Centre (2020)
  • SingHealth Associate in Education (2022 – present)
  • Khoo Scholar, Khoo Scholars’ Programme (KSP), Duke-NUS Medical School (2020 – 2022)


  • ​Outstanding Educator Award, SNEC-SERI Educator Awards, 2022
  • Inspiring Resident Educator Award, SingHealth RiSE Awards, 2022
  • Best Free Paper Oral Award (1st Place), 36th Malaysia-Singapore Joint Ophthalmic Congress (MSJOC) 2022
  • Richard Fan Gold Medal Award for Outstanding Senior Resident 2022
  • Gold Medal, Cataract, Ophthalmology Exit Examination 2022
  • Gold Medal, Generic Issues, Ophthalmology Exit Examination 2022
  • Best Poster Award, Clinical Research (Senior) Category, SingHealth Duke-NUS Scientific Congress, 2021
  • Best Poster Award, General Category, 33rd APACRS-SNEC 30th Anniversary Virtual Meeting, 2021
  • Outstanding Chief Resident Award, Singapore Chief Residency Programme (SCRP), 2021
  • Outstanding Resident Award, SingHealth RiSE Awards, 2021
  • Young Educator Award (Senior Resident), SNEC-SERI Educator Awards, 2021
  • Programme Excellence Award, "Duke-NUS SNEC Basic Certificate for Ophthalmic Assistant and Technician", SingHealth Duke-NUS Golden Apple Awards, 2021
  • Master of Medicine (Ophthalmology) Medal, 2020
  • Khoo Scholars’ Programme, Duke-NUS Medical School, Aug 2020 – Jan 2022
  • Inspiring Resident Educator Award, SingHealth RiSE Awards, 2020
  • Outstanding Resident Award, SingHealth RiSE Awards, 2019
  • Best Scientific Paper Award, 34th APAO Congress, 2019
  • Outstanding Resident Award, SingHealth RiSE Awards, 2016
  • Best House Officer Award, SingHealth Best Junior Doctors Awards, 2015
  • Yeoh Khuan Joo Gold Medal (Top student in Surgery in the Yong Loo Lin School of Medicine Final Professional MBBS Examination), 2014
  • Singapore Medical Association Bronze Medal (2nd place in the Yong Loo Lin School of Medicine Final Professional MBBS Examination), 2014
  • Nihal Kaur Sidhu Medal in Obstetrics and Gynaecology (Top student in Obstetrics and Gynaecology for the degrees of MBBS), 2014
  • Nihal Kaur Memorial Medal (1st place in the Yong Loo Lin School of Medicine Fourth Professional Examination) 2013
  • Gold Medal and Book Prize in Ophthalmology, 2013
  • S.S. Ratnam Book Prize (Top student in Obstetrics & Gynaecology), 2013

Research Interests


  1. Tan TE, Finkelstein MT, Tan GSW, Tan ACS, Chan CM, Mathur R, Wong EYM, Cheung CMG, Wong TY, Milea D, Najjar RP. Retinal neural dysfunction in diabetes revealed with handheld chromatic pupillometry. Clin Exp Ophthalmol 2022.
  2. Tan TE, Fenner BJ, Barathi VA, Tun SBB, Wey YS, Tsai ASH, Su X, Lee SY, Cheung CMG, Wong TY, Mehta JS, Teo KYC. Gene-Based Therapeutics for Acquired Retinal Disease: Opportunities and Progress. Frontiers in Genetics 2021;12:2480.
  3. Fenner BJ, Tan TE, Barathi AV, Tun SBB, Wey YS, Tsai ASH, Lee SY, Cheung CMG, Chan CM, Mehta JS, Teo KYC. Gene-Based Therapeutics for Inherited Retinal Diseases. Frontiers in Genetics 2021;12:794805.
  4. Foo LL, Ng WY, Lim GYS, Tan TE, Ang M, Ting DSW. Artificial intelligence in myopia: current and future trends. Curr Opin Ophthalmol 2021;32:413–424.
  5. Ng WY, Tan TE, Movva PVH, Fang AHS, Yeo KK, Ho D, Foo FSS, Xiao Z, Sun K, Wong TY, Sia ATH, Ting DSW. Blockchain applications in health care for COVID-19 and beyond: a systematic review. Lancet Digit Health 2021:S2589-7500(21)00210–7.
  6. Lim HB, Tan TE, Fenner BJ, Heah J, Arundhati A, Khor WB, Boey PY, Lee SY, Wong EYM, Wong TY. Clinical operational considerations and responses to lockdown and reopening in the Covid-19 pandemic: experience of a tertiary ophthalmology centre in Singapore. Eye (Lond) 2021.
  7. Tan TE, Chodosh J, McLeod SD, Parke DW, Yeh S, Wong TY, Ting DSW. Global Trends in Ophthalmic Practices in Response to COVID-19. Ophthalmology. 2021 Aug 17;S0161-6420(21)00559-5.
  8. Ng WY, Tan TE, Xiao Z, Movva PVH, Foo FSS, Yun D, Chen W, Wong TY, Lin HT, Ting DSW. Blockchain Technology for Ophthalmology: Coming of Age? Asia Pac J Ophthalmol (Phila) 2021;10:343–347.
  9. Tan TE, Wong TY, Ting DSW. Artificial Intelligence for Prediction of Anti-VEGF Treatment Burden in Retinal Diseases: Towards Precision Medicine. Ophthalmol Retina. 2021 Jul;5(7):601–3.
  10. Tan TE, Chan HW, Singh M, Wong TY, Pulido JS, Michaelides M, Sohn EH, Ting D. Artificial intelligence for diagnosis of inherited retinal disease: an exciting opportunity and one step forward. Br J Ophthalmol 2021; published online May 24. DOI:10.1136/bjophthalmol-2021-319365.
  11. Tan TE, Anees A, Chen C, Li S, Xu X, Li Z, Xiao Z, Yang Y, Lei X, Ang M, Chia A, Lee SY, Wong EYM, Yeo IYS, Wong YL, Hoang QV, Wang YX, Bikbov MM, Nangia V, Jonas JB, Chen Y-P, Wu W-C, Ohno-Matsui K, Rim TH, Tham Y-C, Goh RSM, Lin H, Liu H, Wang N, Yu W, Tan DTH, Schmetterer L, Cheng C-Y, Chen Y, Wong CW, Cheung GCM, Saw S-M, Wong TY, Liu Y, Ting DSW. Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study. Lancet Digit Health 2021; 3: e317–29.
  12. Tan TE, Xu X, Wang Z, Liu Y, Ting DSW. Interpretation of artificial intelligence studies for the ophthalmologist. Curr Opin Ophthalmol. 2020 Sep;31(5):351–6.
  13. Tan TE, Ting DSW, Wong TY, Sim DA. Deep learning for identification of peripheral retinal degeneration using ultra-wide-field fundus images: is it sufficient for clinical translation? Ann Transl Med 2020, May;8(10):611.
  14. Tan TE, Devarajan K, Seah X-Y, Lin S-J, Peh GSL, Cajucom-Uy HY, Ang M, Mehta JS, Tan DTH. Descemet Membrane Endothelial Keratoplasty With a Pull-Through Insertion Device: Surgical Technique, Endothelial Cell Loss, and Early Clinical Results. Cornea 2020, 39(5):558-65.
  15. Ting DSW, Foo VHX, Tan TE, Sie NM, Wong CW, Tsai ASH, Tan GSW, Lim LS, Yeo IYS, Wong DWK, Ong SG, Wong EYM, Ang CL, Lee SY. 25-years Trends and Risk factors related to Surgical Outcomes of Giant Retinal Tear-Rhegmatogenous Retinal Detachments. Sci Rep 2020, 25;10(1):5474.
  16. Yip MYT, Lim G, Lim ZW, Nguyen QD, Chong CCY, Yu M, Bellemo V, Xie Y, Lee XQ, Hamzah H, Ho J, Tan TE, Sabanayagam C, Grzybowski A, Tan GSW, Hsu W, Lee ML, Wong TY, Ting DSW. Technical and imaging factors influencing performance of deep learning systems for diabetic retinopathy. NPJ Digit Med 2020;3:40.
  17. Tan TE, Devarajan K, Seah XY, Lin SJ, Peh GSL, Cajucom-Uy HY, Ang MHN, Tan DTH. Lamellar Dissection Technique for Descemet Membrane Endothelial Keratoplasty Graft Preparation. Cornea 2020, 39(1):23-9.
  18. Tan TE, Nguyen Q, Chua J, Schmetterer L, Tan GSW, Wong CW, Tsai A, Cheung GCM, Wong TY, Ting DSW. Global Assessment of Retinal Arteriolar, Venular and Capillary Microcirculations Using Fundus Photographs and Optical Coherence Tomography Angiography in Diabetic Retinopathy. Sci Rep 2019;9(1):11751.
  19. Tan TE, Tan DTH. Cytomegalovirus Corneal Endotheliitis After Descemet Membrane Endothelial Keratoplasty. Cornea 2019, 38(4):413-418.
  20. Tan TE, Liu YC, Jayasinghe LS, Mehta JS. Intraoperative Optical Coherence Tomography Vault Measurement in Posterior Chamber Phakic Intraocular Lens Implantation. J Refract Surg 2017, 33(4):274-277.

Research Trials