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Clin Assoc Prof Rahat Husain

Clin Assoc Prof Husain Rahat

​MBBS, FRCOphth, MD(Res), FAMS

Senior Consultant

Singapore National Eye Centre

Specialty: Glaucoma, Cataract & Comprehensive Ophthalmology

Sub-specialties: Glaucoma, Cataract & Comprehensive Ophthalmology

Conditions Treated by this Doctor:
Cataract Surgery, Glaucoma.

Clinical Appointments

  • Senior Consultant Glaucoma Department Singapore National Eye CentreSingapore National Eye Centre
  • Senior Consultant Cataract & Comprehensive Ophthalmology Department Singapore National Eye CentreSingapore National Eye Centre
  • Senior Consultant SNEC Eye Clinic @ CGH Changi General HospitalChangi General Hospital

Academic Appointments

  • Deputy Vice-Chair, Regional / Community Eye Care, Ophthalmology and Visual Sciences Academic Clinical Programme (EYE ACP) SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme
  • Clinical Associate Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


Clinical Associate Professor Husain is the current Director of Regional and Community Eye Care for SingHealth, as well as being a Senior Consultant at Singapore National Eye Centre (Glaucoma Department) and Changi General Hospital. He was the previous Head of the eye service at CGH.  He qualified from University College London Medical School and completed basic surgical training in the south of England. From 2002 to 2004 he was employed by the Institute of Ophthalmology (London) as a Clinical Research Fellow at Singapore National Eye Centre where he ran the Singapore 5-Fluorouracil Trabeculectomy Study. This large study examined the natural history of glaucoma surgery and in particular examined the effects of an anti-scarring agent on surgical outcomes. He was also involved in other research projects in patients with primary angle closure glaucoma, namely the Angle Closure Natural History Study and the ACLIPS study. Whilst in Singapore, he also took part in several epidemiological surveys in Indonesia to describe the prevalence and causes of low vision and cataract in that group of people. He returned to England to complete his higher surgical training and went on the gain specialist fellowship training in glaucoma at St Thomas’ and Kings College Hospitals, London.

Clinical Associate Professor Husain has published numerous articles and given many presentations, mainly on the subject of glaucoma and recently has focused on the interaction between glaucoma surgery and cataract surgery.


  • FAMS (2018)
  • MD(Res) (2010)
  • FRCOphth (2009)
  • MBBS (1995)

Professional Appointments and Committee Memberships

  • ​Senior Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore
  • Member, Education Research Working Committee, Singapore National Eye Centre (2018)
  • Associate Program Director, Ophthalmology Residency Programme, SingHealth
  • Member, Outpatient Committee, Singapore National Eye Centre (2015 - present)
  • Member, Quality Assurance Committee, Singapore National Eye Centre (2013 - present)
  • Member, Medical Audit Committee, Changi General Hospital (2014 - 2017)


  • Most Passionate Educator, Residency in SingHealth Excels (RiSE) Award (2012)
  • Gold Award, Singapore Health Quality Service Award, SingHealth (2011 - 2012)
  • Best paper award, glaucoma section, American Academy of Ophthalmology (AAO) meeting (2010)
  • Best presentation award, Southern Ophthalmology Society, UK (2009)
  • Silver Award, Singapore Health Quality Service Award, SingHealth (2009 - 2010)

Research Interests


  1. Longitudinal changes in anterior chamber depth and axial length in Asian subjects after trabeculectomy surgery. Husain R, Li W, Gazzard G, Foster P, Chew P, Oen F, Phillips R, Khaw P, Seah S, Aung T Br J Ophthalmol. Br J Ophthalmol. 2013 Jul;97(7):852-6

  2. Evaluation of choroidal thickness, intraocular pressure and serum osmolality after the water drinking test in eyes with primary angle-closure. Nongpiur ME, Foo V, De Leon JM, Baskaran M, Tun TA, Husain R, Perera SA, Aung T. Invest Ophthalmol Vis Sci. 2015 Mar 5. pii: IOVS-14-15280. doi: 10.1167/iovs.14-15280

  3. A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.  Nat Genet. 2015 Feb 23. doi: 10.1038/ng.3226.  Aung T et al

  4. Lamina cribrosa visibility using optical coherence tomography: comparison of devices and effects of image enhancement techniques. Girard MJ, Tun TA, Husain R, Acharyya S, Haaland BA, Wei X, Mari JM, Perera SA,   Baskaran M, Aung T, Strouthidis NG.Invest Ophthalmol Vis Sci. 2015 Jan 15;56(2):865-74

  5. Swept-source optical coherence tomography assessment of iris-trabecular contact after phacoemulsification with or without goniosynechialysis in eyes with primary angle closure glaucoma. Tun TA, Baskaran M, Perera SA, Htoon HM, Aung T, Husain R.Br J Ophthalmol. 2015 Jan 8. pii: bjophthalmol-2014-306223

  6. The role of lens extraction in the current management of primary angle-closure glaucoma. Trikha S, Perera SA, Husain R, Aung T.Curr Opin Ophthalmol. 2015 Mar;26(2):128-34

  7. A common variant near TGFBR3 is associated with primary open angle glaucoma. Hum Mol Genet. 2015 Jul 1;24(13):3880-92. Li Z et al

  8. Evaluation of primary angle-closure glaucoma susceptibility loci in patients with early stages of angle-closure disease. Nongpiur ME, et al. Ophthalmology. 2018 Jan 5. pii: S0161-6420(17)31588-9

  9. Social, health and ocular factors associated with primary open-angle glaucoma amongst Chinese Singaporeans. Chiam N, Baskaran M, Li Z, Perera S, Goh D, Husain R, Khor CC, Cheng CY, Aung T, Vithana EN. Clin Exp Ophthalmol. 2017 Jun 16

  10. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Aung T et al. Nat Genet. 2017 Jul;49(7):993-1004

  11. Aqueous outflow facility after phacoemulsification with or without goniosynechialysis in primary angle closure: a randomised controlled study. Rodrigues IA, Alaghband P, Beltran Agullo L, Galvis E, Jones S, Husain R, Lim KS. Br J Ophthalmol. 2017 Jul;101(7):879-885

  12. Visual field progression in patients with primary angle-closure glaucoma using pointwise linear regression analysis. Verma S, Nongpiur ME, Atalay E, Wei X, Husain R, Goh D, Perera SA, Aung T. Ophthalmology. 2017 Jul;124(7):1065-1071

  13. Investigation of the variability of anterior chamber scan protocol with cirrus high definition optical coherence tomography. Tun TA, Tan SS, Atalay E, Verma S, Nongpiur ME, Baskaran M, Aung T, Husain R.Clin Exp Ophthalmol. 2017 Jul;45(5):464-471

  14. Evaluation of the anterior segment angle-to-angle scan of cirrus high-definition optical coherence tomography and comparison with gonioscopy and with the Visante OCT. Tun TA, Baskaran M, Tan SS, Perera SA, Aung T, Husain R. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):59-64

  15. Pattern of visual field loss in primary angle-closure glaucoma across different severity levels. Atalay E, Nongpiur ME, Yap SC, Wong TT, Goh D, Husain R, Perera SA, Aung T. Ophthalmology. 2016 Sep;123(9):1957-64

  16. Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Khor CC et al. Nat Genet. 2016 May;48(5):556-62

  17. Glaucoma: surgical treatments and anti-scarring strategies Clarke J, Sangermani C, Husain R, Khaw P. Postgraduate Doctor Journal, August 2003

  18. A review of trabeculectomy in East Asian people – the influence of race.  Husain R, Clarke J, Seah S, Khaw P.  Eye 2005 89(3):288-90

  19. The management of patients with cataracts and medically uncontrolled glaucoma. Husain R. Med Hypothesis Discov Innov Ophthalmol. 2014 Spring;3(1):20-30. Review

  20. Effect of prostaglandin analogue use on the development of cystoid macular edema after phacoemulsification using STROBE statement methodology. Hernstadt DJ, Husain R. J Cataract Refract Surg. 2017 Apr;43(4):564-569

Research Trials