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Prof Dan Milea

Prof Milea Dan

MD, PhD (Paris)

Senior Clinician

Singapore National Eye Centre

Specialty: Neuro-Ophthalmology

Clinical Interest: Neuro-Ophthalmology

Clinical Appointments

  • Senior Consultant Neuro-Ophthalmology Department Singapore National Eye CentreSingapore National Eye Centre

Academic Appointments

  • Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


Professor Dan Milea is a Neuro-ophthalmologist and a senior consultant who holds a MD and a PhD in Neuroscience from the University of Pierre et Marie Curie, Paris, France. He was successively a Neuro-Ophthalmology consultant at the Pitie Salpetriere University Hospital in Paris, then a Professor of Neuro-Ophthalmology in Copenhagen, Denmark, before being the Chairman and Professor of Ophthalmology at the Angers University Hospital, France. In Singapore since 2012, he is currently a Senior Clinician in the Department of Neuro-ophthalmology at SNEC. He has published over 150 articles in peer-reviewed journals and he is a Principal Investigator for several studies in Clinical Neuro-Ophthalmology and Visual Neuroscience.  
Professor Milea is also a member of the faculty staff at Duke-NUS Graduate Medical School, and Head of the Visual Neuroscience group at the Singapore Eye Research Institute. He is involved in the Neuro-Ophthalmology teaching programmes and mentoring of residents, trainees and research staff.


  • PhD (Paris) (2003)
  • MD (1997)

Professional Appointments and Committee Memberships

​Member, Research Committee, Singapore National Eye Centre (2014 – present)


Research Interests

  • Clinical Research in Neuro-Ophthalmology
  • Eye Movements and Pupillary Responses to Light
  • Visual Neuroscience, Non-image forming functions of the eye


  1. Najjar RP, Sharma S, Atalay E, Rukmini A, Sun C, Lock JZ, Mani B, Perera S, Husain R, Lamoureux E, Gooley J, Aung T, Milea D. Pupillary responses to full-field chromatic stimuli are reduced in patients with early-stage primary open-angle glaucoma. Ophthalmology, 2018, in press

  2. Teo KY, Tow SL, Haaland B, Gosavi TD, Loo JL, Lo YL, Milea D. Low conversion rate of ocular to generalized myasthenia gravis in Singapore. Muscle Nerve. 2017 Oct 5 

  3. Tan ACS, Tan GS, Denniston AK, Keane PA, Ang M, Milea D, Chakravarthy U, Cheung CMG. An overview of the clinical applications of optical coherence tomography angiography. Eye (London), 2017, Sept 8

  4. Sharma S, Ang M, Najjar RP, Sng C, Cheung C, Milea D. Optical coherence tomography angiography in acute non-arteritic anterior ischemic optic neuropathy. Br J Ophthalmol. 2017 Aug;101(8):1045-1051 

  5. Rukmini AV, Najjar RP, Atalay RP, Sharma S, MD, Lock JZ, Mani B, Nongpiur M, Aung T, Milea D. Pupillary responses to light are not affected by narrow irido-corneal angles.  Sci Rep, 2017, 31(7): 10190 

  6. Lo YL, Najjar RP, Milea D. Diagnostic tests for myasthenia gravis with ocular involvement. J Neurol Sci. 2017 Aug 15;379:338

  7. Najjar RP, Sharma S, Drouet M, Leruez S, Baskaran M, Nongpiur ME, Aung T, Fielding J, White O, Lamirel C, Milea D. Disrupted Eye Movements in Preperimetric Glaucoma. Invest Ophthalmol Vis Sci, 2017 Apr 1;58(4):2430-2437 

  8. Lo YL, Najjar RP, Teo KY, Tow S, Loo JL, Milea D. A reappraisal of diagnostic tests for myasthenia gravis in a large Asian cohort. J Neurol Sci, 2017, May 15;376:153-158

  9. Loo JL, Singhal S, Tow S, Amati-Bonneau P, Procaccio V, Bonneau D, Reynier P, Ferre M, Milea D. Multi-ethnic involvement in autosomal dominant optic atrophy in Singapore. Eye (London), 2017 Mar;31(3):475-480

  10. Rukmini AV, Milea D, Aung T, Gooley J. Pupillary responses to short-wavelength light are preserved in aging. Sci Reports, 2017, March 7 

  11. Yong Z, Hsieh PJ, Milea D. Seeing the sound after visual loss: functional MRI in acquired auditory-visual synesthesia. Exp Brain Res, 2017 Feb;235(2):415-420 

  12. Hung SM, Milea D, Viénot F, Rukmini DV, Najjar R, Tan JH, Dubail M, Tow SLC, Aung T, Gooley JJ, Hsieh PJ. Neural correlates of melanopic-mediated retinal photoreception. NeuroImage, 2017 Feb 1;146:763-769 

  13. Najjar R, Milea D. Can photoreceptor loss also account for changes in pupil size following panretinal photocoagulation? Eye (London), 2017, 235(2) :415-420 

Research Trials

  • Chromatic pupillometry in glaucoma 
  • Eye movements in ophthalmic conditions
  • Neurobiology of Myopia
  • Hereditary optic neuropathies