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Nicotine

Drug Class: Commonly Known As: Category:
Nicotine Nicotinell® Adult

Nicotine - What is it for

​Nicotine Replacement Therapy (NRT) delivers nicotine without the other harmful chemicals present in cigarette smoke. It reduces the withdrawal symptoms experienced when you are trying to quit smoking, allowing you to focus on the other aspects in your effort to quit smoking.
Nicotinell® Lozenge dissolves in the mouth to release a dose of nicotine to reduce your urge to smoke.

Nicotine - Side Effects, Precautions, and Contraindications

What side effects can Nicotine cause?

  • Throat irritation
  • Jaw ache
  • Increased salivation
  • Hiccups
  • Dry mouth
  • Flatulence
  • Stomach discomfort
  • Heartburn
  • Nausea and vomiting
  • Dizziness
  • Headache

These side effects usually occur as a result of intense sucking of lozenges. Suck the lozenge slowly and take longer breaks in between lozenges to reduce these side effects.


The symptoms of a drug allergy include one or more of the following: 

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

Before taking Nicotine, what precautions must I follow?

​You should stop smoking once you start to use NRT. Smoking and using NRT at the same time may increase the risk of adverse effects from the additive effects of nicotine in your body.
If you continue to feel the urge to smoke or experience severe nicotine withdrawal symptoms even after using the NRT lozenges, please inform your healthcare professional as you may need other types of NRT.
Inform your healthcare professional if:

  • You are pregnant, planning to become pregnant, or breastfeeding.
  • You recently had a heart attack or stroke.
  • You have active peptic ulcer disease.
  • You have any other medical conditions.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.
  • You are less than 18 years old.

What food or medicine must I avoid when I take Nicotine?

  • ​Avoid coffee, tea, juices, acidic and fizzy drinks 15 minutes before and during use of nicotine lozenge as this may reduce nicotine absorption.
  • Nicotine may reduce the effect of certain medications. When NRT dose is reduced or stopped, adjustments to these medications may be necessary.
  • These medications include:
    • Benzodiazepines (e.g. diazepam, lorazepam)
    • Insulin
    • Beta-blocker (e.g. bisoprolol, atenolol)
    • Opioid painkillers (e.g. codeine)
  • Inform your doctor or pharmacist about other medications – including over-the-counter medications, supplements and traditional/herbal remedies – that you are currently taking as they may affect the way you benefit from NRT.

Nicotine - Dosage and How to Use

How should Nicotine be used?

​When you feel the urge to smoke, suck one lozenge to release a peppery taste then park the lozenge between your cheek and gum. Resume sucking the lozenge when the taste has faded. Repeat for about 30 minutes until the lozenge completely dissolves. You can suck on one lozenge every 1-2 hours.

Do not chew or swallow the lozenge.

Do not use more than the recommended maximum number of lozenges as instructed by your healthcare professional or use more than one lozenge each time.

What should I do if I miss a dose?

What should I do if I overdose?

If you take more than the recommended dose, please seek medical advice immediately.

Nicotine - Handling

How should I handle Nicotine safely?

Nicotine - Storage

How should I store Nicotine?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

How should I dispose of Nicotine safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Nicotine - Additional Information

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

    ​If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

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