Grants FY22-23

NMRC

• “Development of a SPARC Silencing Delivery System: A Targeted Approach for Treating Fibrosis Following Glaucoma Filtration Surgery”
  Prof Tina Wong; S$208,333.00
• “Prognostic Significance of Novel Multimodal Imaging for Diabetic Retinopathy: Can we Improve Diabetic Retinopathy Staging?”
  Assoc
  Prof Gavin Tan; S$675,000.00
• “Evaluation of an Intraocular Delivery System for VEGF siRNA in Treating Retinal Disorders”
  Assoc Prof Wang Xiaomeng; S$229,420.58
• “Testing the Role of Peripheral Scleral and Choroidal Remodelling in Low, High and Pathologic Myopia”
  Assoc Prof Donny Hoang; S$674,995.00
• “TAckling & Reducing Glaucoma Blindness with Emerging Technologies (TARGET)”
  Prof Aung Tin; S$19,230,769.00
• “Tackling Fibrosis in Glaucoma Surgery (FiGS)”
  A/Prof Tina Wong; S$1,726,000.00
• “AI-Assisted Visual Impairment Screening Model: Community-based Implementation and Evaluation of Performance, Feasibility and Costs”
  Dr Tham Yih Chung; S$500,000.00
• “Investigation of Drug Induced Toxic Optic Neuropathy using Human Stem Cell Derived Retinal Ganglion Cells”
  Dr Shweta Singhal; S$675,000.00
• “Dopamine treatment of Myopia (DTOM): Assessing the efficacy of levodopa eye drops in the control of childhood myopia”
  Assoc Prof Audrey Chia; S$1,215,487.69
• “Evaluating the REal-World PAtient-ReporteD and Economic Impact of Combined PHACO-MIGS Surgery (REWARD)”
  Dr Ryan Man; S$499,999.99
• “Simple Non-cultured Endothelial Cell (SNEC) Replacement Therapy for the Treatment of Corneal Endothelial Dysfunction”
  Prof Jodhbir Mehta; S$1,432,359.26
• “The SenseHealth Research Programme: Untangling the Complex Relationship Between the Severity/Laterality of Age-related Sensory Decline, and Frailty in Elderly Singaporeans Through Novel Risk Factors, Non-invasive biomarkers, patient-centred impact, and Potential Intervention Targets to Improve Frailty Outcomes”
  Prof Ecosse Lamoureux; S$1,749,903.48

A*Star/ Duke-NUS/ MOH/ Others

• “Development of Antifungal Contact Lenses for Fusarium Keratitis”
  Dr Venkatesh Mayandi; S$150,000.00
• “Evaluate a Novel Therapeutic Molecule for the Treatment of Ocular Angiogenic Diseases”
  Assoc Prof Wang Xiaomeng; S$624,030.00
• “Development of an Artificial Intelligence-Enabled Digital Platform for The Prediction of High Myopia in Singapore Children”
  Assoc Prof Marcus Ang; S$464,464.00
• “Development of Nanocarrier Platform for siRNA/mRNA Therapeutics”
  Prof Tina Wong; S$74,930.00
• “Development of a Personalized Medicine Strategy for Age-related Macular Degeneration (AMD) Therapeutic”
  Dr Simon Nusinovici; S$58,000.00
• “Optic Nerve Head Perfusion in a Murine Model of Pathological Myopia”
  Dr Rachel Chong; US$60,000.00
• “Promoting Neurorecovery in Mouse Retail Ganglion Cells”
  Prof Jonathan Crowston; S$150,000.00

SingHealth

• “Tools to Improve Psychological Symptoms for Patients with Dry Eye Disease (TIPS-DED) in Primary Care”
  Dr Leong Yuan Yuh; S$65,000.00

Commercial

• “A Phase IIIb/IV, Multicenter, Open-label, Single-Arm Study to Investigate the Efficacy and Safety of Faricimab (RO6867461) in Patients with Polypoidal Choroidal Vasculopathy - SALWEEN”
  Prof Gemmy Cheung; S$163,855.44
• “Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients with Complex Corneas”
  Prof Jodhbir Mehta; S$193,676.97
• “Randomized allocation, Single Blindness, Retrospective Clinical Trial of “iDMas-DR” and “iDMas-AMD”
  Prof Gemmy Cheung; S$40,950.21
• “Anti-scarring Agent Phase II: The Anti-fibrotic Agent Valproic Acid for Bleb Maintenance for Microshunt”
  Prof Tina Wong; S$260,468.50
• “PSVue®, A Molecular Apoptosis Marker for In-vivo Imaging in Retinal Diseases”
  Assoc Prof Amutha Barathi; S$76,662.61