“Retinal Microvascular Changes in Pre-diabetes: Predicting the Progression to Diabetes and Evaluating the Response to Exercise. The Pre-DICTED EYE Study”
Assoc Prof Gavin Tan; S$1,046,472.00“Revisiting the Structure/Function Relationship in Glaucoma for Improved Patient Care”
Prof Leopold Schmetterer; S$1,249,913.00
• “Developing Hyperspectral OCT as a Clinical Test to Detect Neural Dysfunction in Degenerative Diseases of the Optic Nerve and Retina”
Prof Leopold Schmetterer; S$5,656,864.95“Personalizing Diabetic Retinopathy Screening Intervals via Risk Stratification using an Artificial Intelligence-enabled Multi-modal Machine Learning Approach”
Assoc Prof Daniel Ting; S$674,995.00“Comparison of Focal Inner and Outer Retina Structure and Function to Accurately Diagnose Glaucoma in High Myopia Eyes”
Dr Rachel Chong; S$312,000.00“SAMURAI (Singapore Advanced Multi-subspeciality Unified Research and Innovation Centre in Ophthalmology)”
Prof Aung Ting, S$20,000,000.00“Healthy living through personalized monitoring of eyelid care”
Prof Louis Tong; S$58,000.00“Novel AI-driven ageing biomarker based on retinal photos for mortality risk stratification”
Prof Cheng Ching-Yu; S$58,000.00“Modulatory effects of mesenchymal stem cells-derived extracellular vesicles on conjunctival innate immune responses to viral infections”
Dr Ong Hon Shing; S$200,000.00“Studying neurorecovery of retinal ganglion cells in ageing after glaucomatous injury”
Dr Katharina Bell; S$199,870.00“An Intensive, Practical, and Personalized Care Planning to Improve Glycemic Control, Clinical, Ocular, And Patient Centred Outcomes in Poorly Controlled Patients with Diabetic Retinopathy”
Prof Ecosse Lamoureux; S$43,323.00“Optimising the assessment of quality of life in glaucoma using item bank and computer adaptive testing systems”
Prof Ecosse Lamoureux; S$75,000.00“Translational program in ocular surface and dry eye”
Prof Louis Tong; S$62,957.53“Investigating the Genetic and Phenotypic Architecture of Advanced Primary Angle Closure Glaucoma for Stratified Disease management”
Dr Monisha Nongpiur; S$75,000.00“An Innovative and Patient-Centric Research Program Targeting the Ageing Singaporeans: The PopulatION HEalth and Eye Disease PRofile in Elderly Singaporeans (PIONEER) Study”
Prof Ecosse Lamoureux; S$100,000.00“Harnessing LOXL1 as a therapeutic candidate for exfoliation syndrome and exfoliation glaucoma”
Prof Aung Tin; S$100,000.00“The Singapore Epidemiology of Eye Diseases (SEED) Study 3 – Prospective multi-ethnic cohort study of 12-year incidence, risk factors, and impact of major age-related eye diseases”
Prof Cheng Ching-Yu; S$99,716.00“Investigating the role of the primary angle closure glaucoma (PACG) susceptibility gene, PLEKHA7 in PLEKHA7-/- mutant rats”
Dr Anita Chan; S$75,000.00“Scleral Biomechanical Properties in Pathologic Myopia and Myopic Glaucoma”
Dr Donny Hoang; S$75,000.00“Targeted Cell-Based Therapeutic Program for Corneal Blindness”
Prof Jodhbir Mehta; S$100,000.00“Optimising Surgical Management and Patient-related Outcomes of Epiretinal Membrane: Predictive Analytics and Randomised Trial”
Dr Cheung Ning; S$75,000.00“Improved Detection of Glaucomatous Structural Damage Using Wide-Field Optical Coherence Tomography”
Dr Jacqueline Chua; S$50,000.00“Singapore Angle Closure Glaucoma Program: From Genetics to Precision Medicine and Therapy”
Prof Aung Tin; S$180,966.00“Using Novel imaging biomarkers to predict Vascular Endothelial Growth Factor inhibitor retreatment load for neovascular Age related Macular Degeneration”
Dr Kelvin Teo; S$50,000.00“Community-based Screening for Pathological Visual Impairment among Elderly Residents using Artificial-Intelligence Integrated Retinal Imaging”
Dr Tham Yih Chung; S$50,000.00“Development and Validation of a Myopia-Specific Item Bank Administered using Computerized Adaptive Testing: The MyoCAT Study”
Dr Ryan Man; S$50,000.00“TAAP: Translational Asian Age-related Macular Degeneration Program”
Prof Gemmy Cheung; S$300,000.00“A study to identify markers of early retinal cell fate commitment in pluripotent stem cells in vitro”
Dr Shweta Singhal; S$50,000.00“Bayesian Machine Learning Approach to Identify Markers of Progression in Primary Angle Closure Glaucoma”
Dr Monisha Nongpiur; S$75,000.00“Rational Design and Effectiveness of Cell-selective Anti-Microbial Peptides (ROADMAP) for Fungal Keratitis”
Assoc Prof Lakshminarayanan Rajamani; S$765,302.00“INTEgRating bRain, Eye And Cardiac Research (INTER-REACH) : How the Scarecrow found a Brain, the Lion Vision to locate Courage and the Tin Man a Heart”
Prof Leopold Schmetterer; S$1,269,000.00“Refinement and Prospective Validation of a Deep Learning Algorithm for Detecting Chronic Kidney Disease Using Retinal Images (RetiKid)”
A/Prof Charumathi Sabanayagam; S$499,775.50“Risk Stratification of Neuropathic Ocular Surface Dysfunction Using Neural Imaging Metrics, Molecular Biomarkers, and Artificial Intelligence”
Dr Liu Yu Chi; S$675,000.00“Widefield and Multi-modal Corneal Imaging to Investigate Corneal Endothelial Cell Loss following Descemet Membrane Endothelial Keratoplasty (DMEK)”
A/Prof Marcus Ang; S$675,000.00“The Singapore Iymphoma Translational Study (SYMPHONY)”
Dr Anita Chan; S$87,000.00
A*Star/ Duke-NUS/ MOH/ Others
“Anti-Infective Nanocoating for Medical Devices”
Assoc Prof Lakshminarayanan Rajamani; S$125,000.00“Digital and Precision Community Screening Platform for Ageing Diseases: Vision, Metabolism and Heart”
Prof Cheng Ching Yu; S$2,199,260.00“MARIO: Multimodal AI-Driven Decision Making for Ophthalmology”
Prof Wong Tien Yin; S$3,245,100.00“The Biomechanical Phenotype of Normal Tension Glaucoma”
Assoc Prof Michael Girard; USD200,000“Artificial Intelligence in Medicine Transformation Program (AIMx)”
Assoc Prof Daniel Ting; S$957,540.00“IMCB-NUS-SERI-XCell Joint lab: RECET (Regenerative Cell Therapies)”
Prof Gemmy Cheung; S$300,000.00“Proteolytic Stability and Bioavailability of Branched Antifungal Peptide”
Assoc Prof Lakshminarayanan Rajamani; S$50,000.00“Artificial Intelligence (AI) and Digital Health”
Assoc Prof Daniel Ting; S$160,000.00“Minimally-invasive Treatment for Chronic Angle Closure Glaucoma”
Assoc Prof Shamira Perera; S$175,200.00“Ocular Biomaterials for Vitreoretinal Therapeutic Applications (OrBiTAl)”
Prof Gemmy Cheung & Prof Tina Wong; S$980,000.00
SingHealth
“Structural Changes of the Optic Nerve Head in Different Body Positions in Subjects with Obstructive Sleep Apnea and Normaltension Glaucoma: A Pilot Study using Optical Coherence Tomography”
Dr Tin Aung Tun; S$50,000.00“3D AI Technologies to Discriminate between Benign Optic Nerve Head Drusen and Potentially Life-threatening Papilledema due to Neurological Disorders”
Assoc Prof Michael Girard; S$80,000.00“Retinal Vascular Imaging in the Healthy Early Life Moments in Singapore (HELMS) Model of Care”
Dr Ng Wei Yan; S$150,000.00“Multi-centre implementation of artificial intelligence (AI)-based eye screening in Singapore”
Dr Dinesh Gunasekeran; S$65,000.00
Commercial
“A Phase IIIB, Global, Multicenter, Randomized, Visual Assessor-masked Study of the Efficacy, Safety, and Pharmacokinetics of a 36-week Refill Regimen for the Port Delivery System with Ranibizumab in Patients with Neovascular Age-related Macular Degeneration (Velodrome)”
Clin Assoc Prof Lee Shu Yen; S$272,020.24“A Multicenter, Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Faricimab in Patients with Diabetic Macular Edema (RHONE-X)”
Assoc Prof Gavin Tan; S$27,528.26“Single Site, Feasibility Study to Evaluate the Safety of the ENDOART® for Treatment of Subjects Suffering from Corneal Edema”
Prof Jodhbir Mehta; S$149,938.71“A Multicenter, Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Faricimab in Patients with Neovascular Age-related Macular Degeneration (Avonelle-X)”
Prof Gemmy Cheung; S$28,517.26“Retro-prospective Evaluation of the Clinical Safety and Effectiveness of Hydrophilic Acrylic Intraocular Lens”
Dr Mohamad Rosman; S$141,641.93“Testing Small Molecule Compound in Laser-induced CNV in Non-Human Primate Model”
Dr Amutha Barathi; S$272,993.49“Direct Selective Laser Trabeculoplasty for Primary Open Angle Glaucoma and Ocular Hypertension in Ethnic Chinese Population The Zhuiguang 追光 Trial”
Assoc Prof Shamira Perera; S$165,595.79“Evaluation of Visual Outcomes in Patients with Complex Corneas Implanted with IC-8 IOL”
Prof Jodhbir Mehta; S$69,993.32“To Establish In-vivo Baseline Efficacy of AAV2-RPE65 Gene Therapy by Subretinal Injection in a Murine Model of RD12 Mice”
Prof Jodhbir Mehta; S$122,028.26“Evaluation of Anti-inflammatory Small Molecule Inhibitor in AKIMBA PDR Model”
Dr Amutha Barathi; S$80,003.37“Clinical Investigation of the Cheetah System for the Correction of Myopic Refractive Errors with and Without Astigmatism”
Prof Jodhbir Mehta; S$613,490.21
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