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Grants FY14-15

NMRC

  • “Development of xanthone-derived antibiotics as therapeutics for multidrug-resistant gram-positive pathogen infections”.
    Dr Liu Shou Ping; S$1,250,000.00

  • “Rational design of synthetic mimics of antimicrobial peptides: From in silico to in vivo”.
    Dr Li Jianguo; S$199,500.00

  • “Singapore age-related macular degeneration genetic architecture (SAGA) study: From population genomics to personalized medicine”.
    A/Prof Cheng Ching-Yu; S$668,071.17

  • “The Singapore colour pupillometry evaluation (SCOPE): A novel detection test for glaucoma”.
    Prof Dan Milea; S$1,035,050.00

  • “Next generation optical coherence tomography (OCT) for the cornea and anterior segments of the eye”.
    Dr Marcus Ang; S$195,829.00

  • “Singapore angle closure glaucoma program: Characterization, prevention and management”.
    Prof Aung Tin; S$5,500,000.00

  • “Neuroglobin in a primate experimental model of glaucoma: A novel neuroprotectant in glaucoma”.
    Dr Anita Chan; S$375,000.00

  • “Assessing placental perfusion and fetal growth by examining maternal retina during pregnancy”.
    Dr Queenie Li Lingjun; S$375,000.00

  • “Randomized controlled trial of lutein as a novel neuroprotective adjunctive therapy to improve visual outcome of rhegmatogenous retinal detachment (LUNAR Trial)”.
    Dr Ning Cheung; S$375,000.00


BMRC

  • “SIPRAD - SERI-IMCB programme in retinal angiogenic diseases”.
    Prof Wong Tien Yin; S$9,900,000.00


A*Star/ Duke-NUS/ MOH/ Others

  • “Roles of regulatory variants for LOXL1 in pseudoexfoliation glaucoma”.
    Prof Aung Tin; S$100,000.00

  • “A novel diabetic macular edema screening model using spectral-domain optical coherence tomography in primary care setting in Singapore”.
    Dr Gavin Tan; S$300,000.00

  • “Retinal microvascular abnormalities as predictors of decline in kidney function in the Singapore Indian eye study cohort”.
    Dr Charumathi Sabanayagam; S$197,398.00

  • “Prevention of and intervention for eye diseases in the elderly [PROVIDE]”.
    Prof Ecosse Lamoureux; S$200,000.00

  • “Improving diabetes and health outcomes: Enhancing health literacy in patients with diabetes and diabetic retinopathy”.
    Prof Ecosse Lamoureux; S$199,750.00

  • “Translational PoC study of RO6897779 in NHP with ocular hypertension”.
    Dr Amutha Barathi Veluchamy; S$147,665.34

  • “ATX in glaucoma – ATX inhibitor study in Dutch belted rabbits”.
    Dr Amutha Barathi Veluchamy; S$75,602.63

  • “Efficacy of bispecific crossmab antibodies in model of laser induced CNV in NHP”.
    Dr Amutha Barathi Veluchamy; S$130,005.38

  • “Validation of a novel micro-fluid cytokine analysis platform for aqueous and vitreous humour in normal and eyes with diabetic retinopathy”.
    Prof Wong Tien Yin; S$176,483.37

  • “Randomised clinical trial of acupuncture and herbal treatment in dry eye: Cutting edge technologies meet traditional Chinese medicine”.
    A/Prof Louis Tong; S$265,634.00

  • “Retina, imaging and epidemiology”.
    Prof Wong Tien Yin; S$1,500,000.00


SingHealth

  • “Rational design of novel branched antimicrobial peptides”.
    Dr Li Jianguo; S$50,000.00

  • “Optimization of anti-tuberculosis molecules by lipid tail modification of cationic amphiphilic a-mangostin derivatives and the membrane-targeting study”.
    Dr Liu Shou Ping; S$150,000.00

  • “Antimicrobial peptide immobilization for preventing peri/post-operative artificial cornea implants associated infection”.
    Dr Gary Yam; S$149,862.00

  • “Tear biomarkers for patients with thyroid orbitopathy”.
    Dr Zhou Lei; S$149,720.00


Commercial

  • “Randomized, double-masked, vehicle controlled clinical evaluation to assess the safety and efficacy of nepafenac ophthalmic suspension, 0.3% for improvement in clinical outcomes among diabetic subjects following cataract surgery”.
    Adj A/Prof Edmund Wong; S$137,305.68

  • “A randomised, double-masked, sham-controlled phase 3b/4 study of the efficacy, safety, and tolerability of intravitreal aflibercept monotherapy compared to aflibercept with adjunctive photodynamic therapy as indicated in subjects with polypoidal choroidal vasculopathy (PLANET)”.
    A/Prof Gemmy Cheung; S$116,736.92

  • “Chronobiological effects of blocking blue light – the BLUES study (blocking light usefully for efficient sleep)”.
    Prof Dan Milea; S$164,056.63

  • “Laser-induced choroidal neovascularization (CNV) in cynomolgus monkeys-age-related macular degeneration (AMD) model”.
    Dr Amutha Veluchamy Barathi; S$431,990.35

  • “Choriodal neovascularization in Asians: Is there a difference in genetic background between age-related macular degeneration and polypoidal chorodial vasculopathy?”
    Prof Wong Tien Yin; S$286,352.95