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Our Publications FY14-15

  1. Tan DK, Tay WT, Chan C, Tan DT, Mehta JS. Postoperative ocular higher-order aberrations and contrast sensitivity: Femtosecond lenticule extraction versus pseudo small-incision lenticule extraction. J Cataract Refract Surg. 2015 Mar;41(3):623-34.

  2. Lim DK, Shen S, Jejah IA, Cullen JF. Unusual optic disc infarction in a case of arteritic anterior ischaemic optic neuropathy (AAION). Singapore Med J. 2015 Mar;56(3):e36-8.

  3. Man RE, Sasongko MB, Xie J, Kawasaki R, Best WJ, Noonan JE, Luu CD, Wang JJ, Lamoureux EL. Associations of retinal oximetry in persons with diabetes. Clin Experiment Ophthalmol. 2015 Mar;43(2):124-31.

  4. Wong CW, Yuen L, Tseng P, Han DC. Outcomes of the Haigis-L formula for calculating intraocular lens power in Asian eyes after refractive surgery. J Cataract Refract Surg. 2015 Mar;41(3):607-12.

  5. Li J, Fine J, Brookhart A. Instrumental variable additive hazards models. Biometrics. 2015 Mar;71(1):122-30.

  6. Springelkamp H, Mishra A, Hysi PG, Gharahkhani P, Höhn R, Khor CC, Cooke Bailey JN, Luo X, Ramdas WD, Vithana E, Koh V, Yazar S, Xu L, Forward H, Kearns LS, Amin N, Iglesias AI, Sim KS, van Leeuwen EM, Demirkan A, van der Lee S, Loon SC, Rivadeneira F, Nag A, Sanfilippo PG, Schillert A, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A; NEIGHBORHOOD Consortium, Zhou T, Burdon KP, Spector TD, Lackner KJ, Saw SM, Vingerling JR, Teo YY, Pasquale LR, Wolfs RC, Lemij HG, Tai ES, Jonas JB, Cheng CY, Aung T, Jansonius NM, Klaver CC, Craig JE, Young TL, Haines JL, MacGregor S, Mackey DA, Pfeiffer N, Wong TY, Wiggs JL, Hewitt AW, van Duijn CM, Hammond CJ. Meta-analysis of genome-wide association studies identifies novel loci associated with optic disc morphology. Genet Epidemiol. 2015 Mar;39(3):207-16.

  7. Chong RS, Martin KR. Glial cell interactions and glaucoma. Curr Opin Ophthalmol. 2015 Mar;26(2):73-7.

  8. Bansal S, Barathi VA, Iwata D, Agrawal R. Experimental autoimmune uveitis and other animal models of uveitis: An update. Indian J Ophthalmol. 2015 Mar;63(3):211-8.

  9. Fenner BJ, Tong L. More to stable tears than thickness of the tear film lipid layer. Invest Ophthalmol Vis Sci. 2015 Mar;56(3):1601.

  10. Pan CW, Dirani M, Cheng CY, Wong TY, Saw SM. The age-specific prevalence of myopia in Asia: A meta-analysis. Optom Vis Sci. 2015 Mar;92(3):258-66.

  11. Sng CC, Barton K. Mechanism and management of angle closure in uveitis. Curr Opin Ophthalmol. 2015 Mar;26(2):121-127.

  12. Oey NE, Leung HW, Ezhilarasan R, Zhou L, Beuerman RW, VanDongen HM, VanDongen AM. A neuronal activity-dependent dual function chromatin-modifying complex regulates arc expression1. eNeuro. 2015 Mar 14;2(1).

  13. McAuley AK, Dirani M, Wang JJ, Connell PP, Lamoureux EL, Hewitt AW. A genetic variant regulating miR-126 is associated with sight threatening diabetic retinopathy. Diab Vasc Dis Res. 2015 Mar;12(2):133-8.

  14. Man RE, Sasongko MB, Wang JJ, Lamoureux EL. Author response: Retinal capillary flow and diabetic retinopathy. Invest Ophthalmol Vis Sci. 2015 Mar;56(3):2002.

  15. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 2015 Mar;24(6):1791-800.

  16. Wong CW, Liao J, Cheung CM, Khor CC, Vithana EN, Wang JJ, Mitchell P, Aung T, Wong TY, Cheng CY. Lens status influences the association between CFH polymorphisms and age-related macular degeneration: Findings from two population-based studies in Singapore. PLoS One. 2015 Mar;10(3):e0119570.

  17. Miyake M, Yamashiro K, Tabara Y, Suda K, Morooka S, Nakanishi H, Khor CC, Chen P, Qiao F, Nakata I, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Meguro A, Kusuhara S, Polasek O, Hayward C, Wright AF, Campbell H, Richardson AJ, Schache M, Takeuchi M, Mackey DA, Hewitt AW, Cuellar G, Shi Y, Huang L, Yang Z, Leung KH, Kao PY, Yap MK, Yip SP, Moriyama M, Ohno-Matsui K, Mizuki N, MacGregor S, Vitart V, Aung T, Saw SM, Tai ES, Wong TY, Cheng CY, Baird PN, Yamada R, Matsuda F; Nagahama Study Group, Yoshimura N. Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia. Nat Commun. 2015 Mar;6:6689.

  18. Chan EW, Chiang PP, Liao J, Rees G, Wong TY, Lam JS, Aung T, Lamoureux E. Glaucoma and associated visual acuity and field loss significantly affect glaucoma-specific psychosocial functioning. Ophthalmology. 2015 Mar;122(3):494-501.

  19. Lim CC, Teo BW, Tai ES, Lim SC, Chan CM, Sethi S, Wong TY, Sabanayagam C. Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in asian adults. PLoS One. 2015 Mar;10(3):e0122009.

  20. Peh GS, Adnan K, George BL, Ang HP, Seah XY, Tan DT, Mehta JS. The effects of Rho-associated kinase inhibitor Y-27632 on primary human corneal endothelial cells propagated using a dual media approach. Sci Rep. 2015 Mar;5:9167.

  21. Zhang L, Albon J, Jones H, Gouget CL, Ethier CR, Goh JC, Girard MJ. Collagen microstructural factors influencing optic nerve head biomechanics. Invest Ophthalmol Vis Sci. 2015 Mar;56(3):2031-42.

  22. Tan TE, Peh GS, Finkelstein EA, Mehta JS. A practical model for economic evaluation of tissue-engineered therapies. Wiley Interdiscip Rev Syst Biol Med. 2015 Mar;7(2):91-100.

  23. Trikha S, Perera SA, Husain R, Aung T. The role of lens extraction in the current management of primary angle-closure glaucoma. Curr Opin Ophthalmol. 2015 Mar;26(2):128-34.

  24. Ghaem Maralani H, Tai BC, Wong TY, Tai ES, Li J, Wang JJ, Mitchell P. Metabolic syndrome and risk of age-related macular degeneration. Retina. 2015 Mar;35(3):459-66.

  25. Wong TY, Ohno-Matsui K, Leveziel N, Holz FG, Lai TY, Yu HG, Lanzetta P, Chen Y, Tufail A. Myopic choroidal neovascularisation: Current concepts and update on clinical management. Br J Ophthalmol. 2015 Mar;99(3):289-296.

  26. Konstantopoulos A, Mehta JS. Conventional versus accelerated collagen cross-linking for keratoconus. Eye Contact Lens. 2015 Mar;41(2):65-71.

  27. Ng WY, Tan GS, Ong PG, Cheng CY, Cheung CY, Wong DW, Mathur R, Chow KY, Wong TY, Cheung CM. Incidence of myocardial infarction, stroke, and death in patients with age-related macular degeneration treated with intravitreal anti-vascular endothelial growth factor therapy. Am J Ophthalmol. 2015 Mar;159(3):557-564.e1

  28. Ang M, Dubis AM, Wilkins MR. Descemet membrane endothelial keratoplasty: Intraoperative and postoperative imaging spectral-domain optical coherence tomography. Case Rep Ophthalmol Med. 2015;2015:506251.

  29. Cunningham ET Jr, Rathinam SR, Albini TA, Chee SP, Zierhut M. Tuberculous uveitis. Ocul Immunol Inflamm. 2015 Feb;23(1):2-6.

  30. Nissen C, Rönnbäck C, Sander B, Herbst K, Milea D, Larsen M, Lund-Andersen H. Dissociation of pupillary post-illumination responses from visual function in confirmed OPA1 c.983A > G and c.2708_2711delTTAG autosomal dominant optic atrophy. Front Neurol. 2015 Feb;6:5.

  31. Chee E, Fong KS, Al Jajeh I, Nassiri N, Rootman J. The association of lacrimal gland inflammation with alopecia areata. Orbit. 2015 Feb;34(1):45-50.

  32. Gupta P, Cheung CY, Saw SM, Bhargava M, Tan CS, Tan M, Yang A, Tey F, Nah G, Zhao P, Wong TY, Cheng CY. Peripapillary choroidal thickness in young Asians with high myopia. Invest Ophthalmol Vis Sci. 2015 Feb;56(3):1475-81.

  33. Rees G, Xie J, Chiang PP, Larizza MF, Marella M, Hassell JB, Keeffe JE, Lamoureux EL. A randomised controlled trial of a self-management programme for low vision implemented in low vision rehabilitation services. Patient Educ Couns. 2015 Feb;98(2):174-81.

  34. Narayanaswamy A, Leung CK, Istiantoro DV, Perera SA, Ho CL, Nongpiur ME, Baskaran M, Htoon HM, Wong TT, Goh D, Su DH, Belkin M, Aung T. Efficacy of selective laser trabeculoplasty in primary angle-closure glaucoma: a randomized clinical trial. JAMA Ophthalmol. 2015 Feb;133(2):206-12.

  35. Shetty R, Ghosh A, Lim RR, Subramani M, Mihir K, A R R, Ranganath A, Nagaraj S, Nuijts RM4, Beuerman R, Shetty R, Das D, Chaurasia SS, Sinha-Roy A, Ghosh A. Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine a. Invest Ophthalmol Vis Sci. 2015 Feb;56(2):738-50.

  36. Rhodes LA, Huisingh C, Johnstone J, Fazio MA, Smith B, Wang L, Clark M, Downs JC, Owsley C, Girard MJ, Mari JM, Girkin CA. Peripapillary choroidal thickness variation with age and race in normal eyes. Invest Ophthalmol Vis Sci. 2015 Feb;56(3):1872-9.

  37. Sabanayagam C, Khoo EY, Lye WK, Ikram MK, Lamoureux EL, Cheng CY, Tan ML, Salim A, Lee J, Lim SC, Tavintharan S, Thai AC, Heng D, Ma S, Tai ES, Wong TY. Diagnosis of diabetes mellitus using HbA1c in Asians: relationship between HbA1c and retinopathy in a multiethnic Asian population. J Clin Endocrinol Metab. 2015 Feb;100(2):689-96.

  38. Seshasai S, Liao J, Toh QC, Cheng CY, Cheung GC, Sethi S, Wong TY, Sabanayagam C. Serum leptin and age-related macular degeneration. Invest Ophthalmol Vis Sci. 2015 Feb;56(3):1880-6.

  39. Shah JM, Han D, Htoon HM, Mehta JS. Intraobserver repeatability and interobserver reproducibility of corneal measurements in normal eyes using an optical coherence tomography-placido disk device. J Cataract Refract Surg. 2015 Feb;41(2):372-81.

  40. Peh GS, Chng Z, Ang HP, Cheng TY, Adnan K, Seah XY, George BL, Toh KP, Tan DT, Yam GH, Colman A, Mehta JS. Propagation of human corneal endothelial cells: A novel dual media approach. Cell Transplant. 2015 Feb;24(2):287-304.

  41. Rooney D, Lye WK, Tan G, Lamoureux EL, Ikram MK, Cheng CY, Kumari N, Zheng YF, Mitchell P, Wang JJ, Wong TY, Sabanayagam C. Body mass index and retinopathy in Asian populations with diabetes mellitus. Acta Diabetol. 2015 Feb;52(1):73-80.

  42. Yip W, Sabanayagam C, Teo BW, Tay WT, Ikram MK, Tai ES, Chow KY, Wong TY, Cheung CY. Retinal microvascular abnormalities and risk of renal failure in Asian populations. PLoS One. 2015 Feb;10(2):e0118076.

  43. Tong L, Zhou XY, Jylha A, Aapola U, Liu DN, Koh SK, Tian D, Quah J, Uusitalo H, Beuerman RW, Zhou L. Quantitation of 47 human tear proteins using high resolution multiple reaction monitoring (HR-MRM) based-mass spectrometry. J Proteomics. 2015 Feb;115:36-48.

  44. Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polašek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimäki T, Kähönen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Pärssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA; CREAM Consortium. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: The CREAM consortium. Hum Genet. 2015 Feb;134(2):131-46.

  45. Gupta P, Jing T, Marziliano P, Cheung CY, Baskaran M, Lamoureux EL, Wong TY, Cheung CM, Cheng CY. Distribution and determinants of choroidal thickness and volume using automated segmentation software in a population-based study. Am J Ophthalmol. 2015 Feb;159(2):293-301.e3.

  46. Khadka J, McAlinden C, Craig JE, Fenwick EK, Lamoureux EL, Pesudovs K. Identifying content for the glaucoma-specific item bank to measure quality-of-life parameters. J Glaucoma. 2015 Jan;24(1):12-9.

  47. Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N, Bolla MK, Wang Q, Dennis J, Sawyer EJ, Cheng T, Tomlinson I, Kerin MJ, Miller N, Marmé F, Surowy HM, Burwinkel B, Guénel P, Truong T, Menegaux F, Mulot C, Bojesen SE, Nordestgaard BG, Nielsen S, Flyger H, Benitez J, Zamora MP, Arias Perez JI, Menéndez P, González-Neira A, Pita G, Alonso MR, Alvarez N, Herrero D, Anton-Culver H, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Müller-Myhsok B, Brauch H, Brüning T, Ko YD; GENICA Network, Tessier DC, Vincent D, Bacot F, Nevanlinna H, Aittomäki K, Blomqvist C, Khan S, Matsuo K, Ito H, Iwata H, Horio A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM; kConFab Investigators; Australian Ovarian Cancer Study Group, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Neven P, Wauters E, Wildiers H, Lambrechts D, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Radice P, Peterlongo P, Manoukian S, Bonanni B, Couch FJ, Wang X, Vachon C, Purrington K, Giles GG, Milne RL, Mclean C, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, Hassan N, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole MJ, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Devilee P, Tollenaar RA, Seynaeve C, Van Asperen CJ, García-Closas M, Figueroa J, Lissowska J, Brinton L, Czene K, Darabi H, Eriksson M, Brand JS, Hooning MJ, Hollestelle A, Van Den Ouweland AM, Jager A, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cross SS, Reed MW, Blot W, Signorello LB, Cai Q, Pharoah PD, Perkins B, Shah M, Blows FM, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Chia KS, Putti TC, Hamann U, Luccarini C, Baynes C, Ahmed S, Maranian M, Healey CS, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, Brennan P, Mckay J, Slager S, Toland AE116, Yannoukakos D117, Shen CY, Hsiung CN, Wu PE, Ding SL, Ashworth A, Jones M, Orr N, Swerdlow AJ, Tsimiklis H, Makalic E, Schmidt DF, Bui QM, Chanock SJ, Hunter DJ, Hein R, Dahmen N, Beckmann L, Aaltonen K, Muranen TA, Heikkinen T, Irwanto A, Rahman N, Turnbull CA; Breast and Ovarian Cancer Susceptibility (BOCS) Study, Waisfisz Q, Meijers-Heijboer HE, Adank MA, Van Der Luijt RB, Hall P, Chenevix-Trench G, Dunning A, Easton DF, Cox A. Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Hum Mol Genet. 2015 Jan;24(1):285-98.

  48. Ferré M, Caignard A, Milea D, Leruez S, Cassereau J, Chevrollier A, Amati-Bonneau P, Verny C, Bonneau D, Procaccio V, Reynier P. Improved locus-specific database for OPA1 mutations allows inclusion of advanced clinical data. Hum Mutat. 2015 Jan;36(1):20-5.

  49. Cheng CY, Yamashiro K, Jia Chen L, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Guan Ong P, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC. New loci and coding variants confer risk for age-related macular degeneration in East Asians. Nat Commun. 2015 Jan;6:6063.

  50. Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S, Beuerman RW. Amino acid modified xanthone derivatives: Novel, highly promising membrane-active antimicrobials for multidrug-resistant gram-positive bacterial infections. J Med Chem. 2015 Jan;58(2):739-52.

  51. Shetty R, Sathyanarayanamoorthy A, Ramachandra RA, Arora V, Ghosh A, Srivatsa PR, Pahuja N, Nuijts RM, Sinha-Roy A, Mohan RR, Ghosh A. Attenuation of lysyl oxidase and collagen gene expression in keratoconus patient corneal epithelium corresponds to disease severity. Mol Vis. 2015 Jan;21:12-25.

  52. Dou QQ, Teng CP, Ye E, Loh XJ. Effective near-infrared photodynamic therapy assisted by upconversion nanoparticles conjugated with photosensitizers. Int J Nanomedicine. 2015 Jan;10:419-32.

  53. Lakshminarayanan R, Chaurasia SS, Murugan E, Venkatraman A, Chai SM, Vithana EN, Beuerman RW, Mehta JS. Biochemical properties and aggregation propensity of transforming growth factor-induced protein (TGFBIp) and the amyloid forming mutants. Ocul Surf. 2015 Jan;13(1):9-25.

  54. Ng JY, Sng CC, Liao J, Aquino MC, Chew P. Glaucoma drainage device exposure in Asian eyes. Clin Experiment Ophthalmol. 2015 Jan;43(1):85-8.

  55. Girard MJ, Dupps WJ, Baskaran M, Scarcelli G, Yun SH, Quigley HA, Sigal IA, Strouthidis NG. Translating ocular biomechanics into clinical practice: Current state and future prospects. Curr Eye Res. 2015 Jan;40(1):1-18.

  56. Sridhar R, Lakshminarayanan R, Madhaiyan K, Amutha Barathi V, Lim KH, Ramakrishna S. Electrosprayed nanoparticles and electrospun nanofibers based on natural materials: applications in tissue regeneration, drug delivery and pharmaceuticals. Chem Soc Rev. 2015 Jan;44(3):790-814.

  57. Ong YT, Hilal S, Cheung CY, Venketasubramanian N, Niessen WJ, Vrooman H, Anuar AR, Chew M, Chen C, Wong TY, Ikram MK. Retinal neurodegeneration on optical coherence tomography and cerebral atrophy. Neurosci Lett. 2015 Jan;584:12-6.

  58. Hilal S, Chai YL, Ikram MK, Elangovan S, Yeow TB, Xin X, Chong JY, Venketasubramanian N, Richards AM, Chong JP, Lai MK, Chen C. Markers of cardiac dysfunction in cognitive impairment and dementia. Medicine (Baltimore). 2015 Jan;94(1):e297.

  59. Rathnasamy G, Sivakumar V, Foulds WS, Ling EA, Kaur C. Vascular changes in the developing rat retina in response to hypoxia. Exp Eye Res. 2015 Jan;130:73-86.

  60. Lam J, Wong TT, Tong L. Ocular surface disease in posttrabeculectomy / mitomycin C patients. Clin Ophthalmol. 2015 Jan;9:187-91.

  61. Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, Rasmussen-Torvik LJ, Grarup N, Ehm MG, Li L, Baldridge AS, Stančáková A, Abrol R, Besse C, Boland A, Bork-Jensen J, Fornage M, Freitag DF, Garcia ME, Guo X, Hara K, Isaacs A, Jakobsdottir J, Lange LA, Layton JC, Li M, Hua Zhao J, Meidtner K, Morrison AC, Nalls MA, Peters MJ, Sabater-Lleal M, Schurmann C, Silveira A, Smith AV, Southam L, Stoiber MH, Strawbridge RJ, Taylor KD, Varga TV, Allin KH, Amin N, Aponte JL, Aung T, Barbieri C, Bihlmeyer NA, Boehnke M, Bombieri C, Bowden DW, Burns SM, Chen Y, Chen YD, Cheng CY, Correa A, Czajkowski J, Dehghan A, Ehret GB, Eiriksdottir G, Escher SA, Farmaki AE, Frånberg M, Gambaro G, Giulianini F, Goddard WA, Goel A, Gottesman O, Grove ML, Gustafsson S, Hai Y, Hallmans G, Heo J, Hoffmann P, Ikram MK, Jensen RA, Jørgensen ME, Jørgensen T, Karaleftheri M, Khor CC, Kirkpatrick A, Kraja AT, Kuusisto J, Lange EM, Lee IT, Lee WJ, Leong A, Liao J, Liu C, Liu Y, Lindgren CM, Linneberg A, Malerba G, Mamakou V, Marouli E, Maruthur NM, Matchan A, McKean-Cowdin R, McLeod O, Metcalf GA, Mohlke KL, Muzny DM, Ntalla I, Palmer ND, Pasko D, Peter A, Rayner NW, Renström F, Rice K, Sala CF, Sennblad B, Serafetinidis I, Smith JA, Soranzo N, Speliotes EK, Stahl EA, Stirrups K, Tentolouris N, Thanopoulou A, Torres M, Traglia M, Tsafantakis E, Javad S, Yanek LR, Zengini E, Becker DM, Bis JC, Brown JB, Adrienne Cupples L, Hansen T, Ingelsson E, Karter AJ, Lorenzo C, Mathias RA, Norris JM, Peloso GM, Sheu WH, Toniolo D, Vaidya D, Varma R, Wagenknecht LE, Boeing H, Bottinger EP, Dedoussis G, Deloukas P, Ferrannini E, Franco OH, Franks PW, Gibbs RA, Gudnason V, Hamsten A, Harris TB, Hattersley AT, Hayward C, Hofman A, Jansson JH, Langenberg C, Launer LJ, Levy D, Oostra BA, O'Donnell CJ, O'Rahilly S, Padmanabhan S, Pankow JS, Polasek O, Province MA, Rich SS, Ridker PM, Rudan I, Schulze MB, Smith BH, Uitterlinden AG, Walker M, Watkins H, Wong TY, Zeggini E; EPIC-InterAct Consortium, Laakso M, Borecki IB, Chasman DI, Pedersen O, Psaty BM, Shyong Tai E, van Duijn CM, Wareham NJ, Waterworth DM, Boerwinkle E, Linda Kao WH, Florez JC, Loos RJ, Wilson JG, Frayling TM, Siscovick DS, Dupuis J, Rotter JI, Meigs JB, Scott RA, Goodarzi MO; EPIC-InterAct Consortium. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 Jan;6:5897.

  62. Hilal S, Saini M, Tan CS, Catindig JA, Dong YH, Holandez RL, Niessen WJ, Vrooman HA, Ting E, Wong TY, Chen C, Venketasubramanian N, Ikram MK. Intracranial stenosis, cerebrovascular diseases, and cognitive impairment in Chinese. Alzheimer Dis Assoc Disord. 2015 Jan-Mar;29(1):12-7.

  63. Shinoj VK, Murukeshan VM, Baskaran M, Aung T. Integrated flexible handheld probe for imaging and evaluation of iridocorneal angle. J Biomed Opt. 2015 Jan;20(1):016014.

  64. Girard MJ, Tun TA, Husain R, Acharyya S, Haaland BA, Wei X, Mari JM, Perera SA, Baskaran M, Aung T, Strouthidis NG. Lamina cribrosa visibility using optical coherence tomography: comparison of devices and effects of image enhancement techniques. Invest Ophthalmol Vis Sci. 2015 Jan;56(2):865-74.

  65. Wong MY, Chen CL, Ong YT, Hilal S, Ikram MK, Kumari N, Yip CC, Venketasubramanian N, Yap P, Seow D, Wong TY, Cheung CY. High prevalence of undiagnosed eye diseases in individuals with dementia. J Am Geriatr Soc. 2015 Jan;63(1):192-4.

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  2. Man RE, Sasongko MB, Xie J, Best WJ, Noonan JE, Lo TC, Wang JJ, Luu CD, Lamoureux EL. Decreased retinal capillary flow is not a mediator of the protective myopia-diabetic retinopathy relationship. Invest Ophthalmol Vis Sci. 2014 Sep;55(10):6901-7.

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  1. Lim FP, Loh BK, Cheung CM, Lim LS, Chan CM, Wong DW. Evaluation of focal choroidal excavation in the macula using swept-source optical coherence tomography. Eye (Lond). 2014 Sep;28(9):1088-94.

  2. Cheung CM, Mohla A, Wong TY. Resolution of persistent pigment epithelial detachment secondary to polypoidal choroidal vasculopathy in response to aflibercept. Eye (Lond). 2014 Sep;28(9):1148-9.

  3. Man Lam S, Tong L, Duan X, Acharya UR, Tan JH, Petznick A, Wenk MR, Shui G. Longitudinal changes in tear fluid lipidome brought about by eyelid-warming treatment in a cohort of meibomian gland dysfunction. J Lipid Res. 2014 Sep;55(9):1959-69.

  4. Mookiah MR, Acharya UR, Koh JE, Chua CK, Tan JH, Chandran V, Lim CM, Noronha K, Laude A, Tong L. Decision support system for age-related macular degeneration using discrete wavelet transform. Med Biol Eng Comput. 2014 Sep;52(9):781-96.

  5. Wang KJ, Jhanji V, Chen J, Law RW, Leung AT, Zhang M, Wang N, Pang CP, Yam GH. Association of transcription factor 4 (TCF4) and protein tyrosine phosphatase, receptor type G (PTPRG) with corneal dystrophies in southern Chinese. Ophthalmic Genet. 2014 Sep;35(3):138-41.

  6. Zhu HY, Ng J, Salleh SM, Aung TT, Htoon MH, Beuerman RW. Moesin expression in fibrosis in the mouse cornea after sterile mechanical trauma or infection. Cornea. 2014 Sep;33(9):973-80.

  7. Ang M, Mehta JS, Chan C, Htoon HM, Koh JC, Tan DT. Refractive lenticule extraction: Transition and comparison of 3 surgical techniques. J Cataract Refract Surg. 2014 Sep;40(9):1415-24.

  8. Lin X, Wang M, Zuo Y, Li M, Lin X, Zhu S, Zheng Y, Yu M, Lamoureux EL. Health literacy, computer skills and quality of patient-physician communication in Chinese patients with cataract. PLoS One. 2014 Sep;9(9):e107615.

  9. Tay E, Chan AS, Luthert PJ, Rose GE. Congenital respiratory epithelial cysts of the orbit: A rare cause of major orbital impairment. Ophthal Plast Reconstr Surg. 2014 Sep-Oct;30(5):e116-9.

  10. Sasaki M, Kawasaki R, Uchida A, Koto T, Shinoda H, Tsubota K, Wong TY, Ozawa Y. Early signs of exudative age-related macular degeneration in Asians. Optom Vis Sci. 2014 Aug;91(8):849-53.

  11. Do T, Hon DN, Aung T, Hien ND, Cowan CL Jr. Bacterial endogenous endophthalmitis in Vietnam: A randomized controlled trial comparing vitrectomy with silicone oil versus vitrectomy alone. Clin Ophthalmol. 2014 Aug;8:1633-40.

  12. Wong TY. How to bridge the "valley of death" between a research discovery and clinical application? Ann Acad Med Singapore. 2014 Aug;43(8):422-4.

  13. Zhang Z, Srivastava R, Liu H, Chen X, Duan L, Kee Wong DW, Kwoh CK, Wong TY, Liu J. A survey on computer aided diagnosis for ocular diseases. BMC Med Inform Decis Mak. 2014 Aug;14:80.

  14. Wong TY. Improving the prediction of hypertensive target organ damage using novel markers: lessons from retinal vascular imaging research. Hypertension. 2014 Aug;64(2):233-4.

  15. Rathnasamy G, Sivakumar V, Rangarajan P, Foulds WS, Ling EA, Kaur C. NF-κB-mediated nitric oxide production and activation of caspase-3 cause retinal ganglion cell death in the hypoxic neonatal retina. Invest Ophthalmol Vis Sci. 2014 Aug;55(9):5878-89.

  16. Ong YT, Hilal S, Cheung CY, Xu X, Chen C, Venketasubramanian N, Wong TY, Ikram MK. Retinal vascular fractals and cognitive impairment. Dement Geriatr Cogn Dis Extra. 2014 Aug;4(2):305-13.

  17. de Korte CE, de Korne DF, Martinez Ciriano JP, Rosenthal JR, Sol K, Klazinga NS, Bal RA. Diabetic retinopathy care-an international quality comparison. Int J Health Care Qual Assur. 2014;27(4):308-19.

  18. Coscas G, Yamashiro K, Coscas F, De Benedetto U, Tsujikawa A, Miyake M, Gemmy Cheung CM, Wong TY, Yoshimura N. Comparison of exudative age-related macular degeneration subtypes in Japanese and French patients: Multicenter diagnosis with multimodal imaging. Am J Ophthalmol. 2014 Aug;158(2):309-318.

  19. Hong J, Yang Y, Wei A, Deng SX, Kong X, Chen J, Girard MJ, Mari JM, Xu J, Sun X. Schlemm's canal expands after trabeculectomy in patients with primary angle-closure glaucoma. Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5637-42.

  20. Noonan JE, Dusting GJ, Nguyen TT, Man RE, Best WJ, Lamoureux EL. Flicker-induced retinal arteriole dilation is reduced by ambient lighting. Invest Ophthalmol Vis Sci. 2014 Aug;55(9):5476-81.

  21. Cheng W, Tian J, Burgunder JM, Hunziker W, Eng HL. Myotonia congenita-associated mutations in chloride channel-1 affect zebrafish body wave swimming kinematics. PLoS One. 2014 Aug;9(8):e103445.

  22. Lin X, Li M, Wang M, Zuo Y, Zhu S, Zheng Y, Lin X, Yu M, Lamoureux EL. Validation of catquest-9SF questionnaire in a Chinese cataract population. PLoS One. 2014 Aug;9(8):e103860.

  23. Teo L, Choo CT. Orbital inflammatory disease in relapsing polychondritis. Orbit. 2014 Aug;33(4):298-301.

  24. Keay L, Palagyi A, McCluskey P, Lamoureux E, Pesudovs K, Lo S, Ivers R, Boufous S, Morlet N, Ng JQ, Stapleton F, Fraser M, Meuleners L. Falls in older people with cataract, a longitudinal evaluation of impact and risk: The FOCUS study protocol. Inj Prev. 2014 Aug;20(4):e7.

  25. Cheung CM, Wong TY. Is age-related macular degeneration a manifestation of systemic disease? New prospects for early intervention and treatment. J Intern Med. 2014 Aug;276(2):140-53.

  26. Saini M, Tan CS, Hilal S, Dong Y, Ting E, Ikram MK, Sharma VK, Chen C. Computer tomography for prediction of cognitive outcomes after ischemic cerebrovascular events. J Stroke Cerebrovasc Dis. 2014 Aug;23(7):1921-7.

  27. Chong EW, Guymer RH, Klein R, Klein BE, Cotch MF, Wang JJ, Shlipak MG, Wong TY. Is renal function associated with early age-related macular degeneration? Optom Vis Sci. 2014 Aug;91(8):860-4.

  28. Riau AK, Poh R, Pickard DS, Park CH, Chaurasia SS, Mehta JS. Nanoscale helium ion microscopic analysis of collagen fibrillar changes following femtosecond laser dissection of human cornea. J Biomed Nanotechnol. 2014 Aug;10(8):1552-62.

  29. Wong TT, Novack GD, Natarajan JV, Ho CL, Htoon HM, Venkatraman SS. Nanomedicine for glaucoma: Sustained release latanoprost offers a new therapeutic option with substantial benefits over eyedrops. Drug Deliv Transl Res. 2014 Aug;4(4):303-309.

  30. Yong KL, Gong T, Nongpiur ME, How AC, Lee HK, Cheng L, Perera SA, Aung T. Myopia in Asian subjects with primary angle closure: implications for glaucoma trends in East Asia. Ophthalmology. 2014 Aug;121(8):1566-71.

  31. Koh V, Yang A, Saw SM, Chan YH, Lin ST, Tan MM, Tey F, Nah G, Ikram MK. Differences in prevalence of refractive errors in young Asian males in Singapore between 1996-1997 and 2009-2010. Ophthalmic Epidemiol. 2014 Aug;21(4):247-55.

  32. Witting N, Mensah A, Køber L, Bundgaard H, Petri H, Duno M, Milea D, Vissing J. Ocular, bulbar, limb, and cardiopulmonary involvement in oculopharyngeal muscular dystrophy. Acta Neurol Scand. 2014 Aug;130(2):125-30.

  33. Ng WY, Cheung CM, Mathur R, Chan CM, Yeo IY, Wong E, Lee SY, Loh BK, Wong D, Wong TY. Trends in age-related macular degeneration management in Singapore. Optom Vis Sci. 2014 Aug;91(8):872-7.

  34. Ang M, Li L, Chua D, Wong C, Htoon HM, Mehta JS, Tan D. Descemet's stripping automated endothelial keratoplasty with anterior chamber intraocular lenses: complications and 3-year outcomes. Br J Ophthalmol. 2014 Aug;98(8):1028-32.

  35. Chin YC, Wong TY, Cheung CM, Cheung CY, Zheng Y, Mitchell P, Huang H, Wang JJ, Ikram MK. Retinal vascular caliber and age-related macular degeneration in an Indian population from Singapore. Ophthalmic Epidemiol. 2014 Aug;21(4):224-9.

  36. Hilal S, Ong YT, Cheung CY, Tan CS, Venketasubramanian N, Niessen WJ, Vrooman H, Anuar AR, Chew M, Chen C, Wong TY, Ikram MK. Microvascular network alterations in retina of subjects with cerebral small vessel disease. Neurosci Lett. 2014 Aug 8;577:95-100.

  37. Wong MHY, Cheung CM, Chee SP, Mathur R. Exudative detachment as a masquerader in hypoalbuminaemic patients. Clin Kidney J. 2014 Aug;7(4):406-10.

  38. Chin YC, Bhargava M, Khor CC, Cheung CM, Wong TY. Polypoidal choroidal vasculopathy and systemic lupus erythematosus. Lupus. 2014;23(3):319-22. Epub 2014 Jan 9.

  39. Hilal S, Saini M, Tan CS, Catindig JA, Dong YH, Leon LB, Niessen WJ, Vrooman H, Wong TY, Chen C, Venketasubramanian N, Ikram MK. Ankle-brachial index, cognitive impairment and cerebrovascular disease in a Chinese population. Neuroepidemiology. 2014;42(2):131-8.

  40. Chiang PP, Lamoureux EL, Shankar A, Tai ES, Wong TY, Sabanayagam C. Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease. BMC Public Health. 2013 Aug;13(1):730.

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  43. Cheung CM, Li X, Cheng CY, Zheng Y, Mitchell P, Wang JJ, Wong TY. Prevalence, racial variations, and risk factors of age-related macular degeneration in Singaporean Chinese, Indians, and Malays. Ophthalmology. 2014 Aug;121(8):1598-603.

  44. Yang K, Wang FH, Liang YB, Wong TY, Wang JJ, Zhan SY, Wang NL. Associations between cardiovascular risk factors and early age-related macular degeneration in a rural Chinese adult population. Retina. 2014 Aug;34(8):1539-53.

  45. Venkatraman SS, Wong TT. How can nanoparticles be used to overcome the challenges of glaucoma treatment? Nanomedicine (Lond). 2014 Jul;9(9):1281-3.

  46. Wong WL, Li X, Li J, Wong TY, Cheng CY, Lamoureux EL. Accounting for standard errors of vision-specific latent trait in regression models. Invest Ophthalmol Vis Sci. 2014 Jul;55(9):5848-54.

  47. Liew G, Wang JJ, Rochtchina E, Wong TY, Mitchell P. Complete blood count and retinal vessel calibers. PLoS One. 2014 Jul;9(7):e102230.

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  1. Lim LS, Ling LH, Ong PG, Foulds W, Tai ES, Wong E, Lee SY, Wong D, Cheung CM, Wong TY. Dynamic responses in retinal vessel caliber with flicker light stimulation in eyes with diabetic retinopathy. Invest Ophthalmol Vis Sci. 2014 Jul;55(8):5207-13.

  2. Graffe A, Beauchet O, Fantino B, Milea D, Annweiler C. Vitamin d and macular thickness in the elderly: An optical coherence tomography study. Invest Ophthalmol Vis Sci. 2014 Jul;55(8):5298-303.

  3. Sigal IA, Wang B, Strouthidis NG, Akagi T, Girard MJ. Recent advances in OCT imaging of the lamina cribrosa. Br J Ophthalmol. 2014 Jul;98 Suppl 2:ii34-9.

  4. Yong AM, Zhao DB, Siew SC, Goh PS, Liao J, Amrith S. Assessment of bony nasolacrimal parameters among Asians. Ophthal Plast Reconstr Surg. 2014 Jul-Aug;30(4):322-7.

  5. Kim YK, Yoo BW, Kim HC, Aung T, Park KH. Relative lens vault in subjects with angle closure. BMC Ophthalmol. 2014 Jul;14:93.

  6. Dou QQ, Liow SS, Ye E, Lakshminarayanan R, Loh XJ. Biodegradable thermogelling polymers: working towards clinical applications. Adv Healthc Mater. 2014 Jul;3(7):977-88.

  7. Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi MO, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Sheu WH, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T, Yuan J, Hwang JY; CHARGE Hematology Working Group, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians. Diabetes. 2014 Jul;63(7):2551-62.

  8. Liu YC, Alvarez Paraz CM, Cajucom-Uy HY, Agahari D, Sethuraman S, Tan DT, Mehta JS. Risk factors for donor endothelial loss in eye bank-prepared posterior lamellar corneal tissue for descemet stripping automated endothelial keratoplasty. Cornea. 2014 Jul;33(7):677-82.

  9. Ang M, Chong W, Huang H, Wong TY, He MG, Aung T, Mehta JS. Determinants of posterior corneal biometric measurements in a multi-ethnic Asian population. PLoS One. 2014 Jul;9(7):e101483.

  10. Tun TA, Baskaran M, Perera SA, Chan AS, Cheng CY, Htoon HM, Sakata LM, Cheung CY, Aung T. Sectoral variations of iridocorneal angle width and iris volume in Chinese Singaporeans: a swept-source optical coherence tomography study. Graefes Arch Clin Exp Ophthalmol. 2014 Jul;252(7):1127-32.

  11. Foo JN, Tan LC, Liany H, Koh TH, Irwan ID, Ng YY, Ahmad-Annuar A, Au WL, Aung T, Chan AY, Chong SA, Chung SJ, Jung Y, Khor CC, Kim J, Lee J, Lim SY, Mok V, Prakash KM, Song K, Tai ES, Vithana EN, Wong TY, Tan EK, Liu J. Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. Hum Mol Genet. 2014 Jul;23(14):3891-7.

  12. Pan XY, Liu SP, Hong Y. Synthesis and properties of fluorenyl–pyridinyl alternatingcopolymers for light-emitting diodes. Polymer International. 2014 Jun;63(6):1105–1111.

  13. Yeo S, Aung HT, Tong L. The association of dry eye symptoms with socioeconomic factors and quality of life. J Clin Res Ophthalmol. 2014 Jun;1:102.

  14. Mitchell P, Bressler N, Doan QV, Dolan C, Ferreira A, Osborne A, Rochtchina E, Danese M, Colman S, Wong TY. Estimated cases of blindness and visual impairment from neovascular age-related macular degeneration avoided in Australia by ranibizumab treatment. PLoS One. 2014 Jun;9(6):e101072.

  15. Cheung CM, Li X, Mathur R, Lee SY, Chan CM, Yeo I, Loh BK, Williams R, Wong EY, Wong D, Wong TY. A prospective study of treatment patterns and 1-year outcome of asian age-related macular degeneration and polypoidal choroidal vasculopathy. PLoS One. 2014 Jun;9(6):e101057.

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  1. Joachim N, Mitchell P, Younan C, Burlutsky G, Cheng CY, Cheung CM, Zheng Y, Moffitt M, Wong TY, Wang JJ. Ethnic variation in early age-related macular degeneration lesions between white Australians and Singaporean Asians. Invest Ophthalmol Vis Sci. 2014 Jun;55(7):4421-9.

  2. Rees G, Chong XL, Cheung CY, Aung T, Friedman DS, Crowston JG, Lamoureux EL. Beliefs and adherence to glaucoma treatment: A comparison of patients from diverse cultures. J Glaucoma. 2014 Jun-Jul;23(5):293-8.

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