Grants FY19-20

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NMRC

• “Scleral Biomechanical Properties in Pathologic Myopia and Myopic Glaucoma”.
  Dr Donny Hoang; S$675,000.00

• “A study to identify markers of early retinal cell fate commitment in pluripotent stem cells in vitro”.
  Dr Donny Hoang; S$675,000.00

• “Computerized Adaptive Testing (CAT) Technologies to Improve Patient-Provider Experience and Healthcare Outcomes for Patients”.
  Prof Ecosse Lamoureux; S$208,333.00

• “Targeted Cell-Based Therapeutic Program for Corneal Blindness”.
  Prof Jodhbir Mehta; S$1,749,347.00

• “Improved Detection of Glaucomatous Structural Damage Using Wide-Field Optical Coherence Tomography”.
  Dr Jacqueline Chua; S$374,992.37

• “Investigating the role of the primary angle closure glaucoma (PACG) susceptibility gene, PLEKHA7 in Plekha7-/- mutant rats”.
  Dr Anita Chan; S$674,999.70

• “Community-based Screening for Pathological Visual Impairment among Elderly Residents using Artificial-Intelligence Integrated Retinal Imaging”.
  Dr Tham Yih Chung; S$375,000.00

• “Investigating the Genetic and Phenotypic Architecture of Advanced Primary Angle Closure Glaucoma for Stratified Disease management”.
  Dr Monisha Nongpiur; $675,000.00

• “Singapore lYMPHoma translatiONal studY (SYMPHONY) - Theme 4: Harnessing computational genomics and integrative machine learning algorithms to advance diagnosis, prognostication and patient stratification for therapy”.
  Dr Anita Chan; S$250,000.00

• “NCID SHORT TERM FELLOWSHIP FY2019 – INCOMING VISIT for A/Prof Ishwar Singh from the School of Pharmacy at University of Lincoln, UK”.
  A/Prof Rajamani Lakshminarayanan; S$7,697.15

• “Bayesian Machine Learning Approach to Identify Markers of Progression in Primary Angle Closure Glaucoma”.
  Dr Monisha Nongpiur; S$770,257.00

• “Development and Validation of a Myopia-Specific Item Bank Administered using Computerized Adaptive Testing: The MyoCAT Study”.
  Dr Ryan Man; S$374,904.00

• “Evaluation of safety and efficacy of subconjunctival injection of liposomal tacrolimus for allergic conjunctivitis”.
  Prof Jodhbir Mehta; S$208,333.33

• “Wireless Miniaturised GonioPEN for irido-corneal imaging”.
  A/Prof Shamira Perera; S$208,333.33

A*Star/ Duke-NUS/ MOH/ Others

• “Promoting Neurorecovery in Mouse Retail Ganglion Cells”.
  Prof Jonathan Crowston; S$750,000.00

• “Whole exome sequencing of Indian subjects with primary angle closure glaucoma”.
  Prof Aung Tin; S$165,000.00

• “Using Epdr1tm1b Knockout (KO) mice to determine the ocular phenotype of primary angle closure glaucoma (PACG) susceptibility gene, EPDR1 and its effects on cellular adhesion related pathways”.
  Dr Anita Chan; S$200,000.00

• “SERI - Johnson & Johnson Vision Care Joint Research Programme for Myopia”.
  A/Prof Audrey Chia; S$9,385,200.00

• “Functional Features of Outer Retinal Dysfunction Detected using Handheld Chromatic Pupillometry”.
  Dr Raymond Najjar; S$149,206.00

• “New Drug Susceptibility Testing and Treatment Strategies for Non-Tuberculosis Mycobacterial Infections”.
  Prof Roger Beuerman; S$50,000.00

• “Innovations in Ocular Imaging”.
  Dr Anthony Kuo; S$75,000.00

• “Automatic Evaluation and Prediction of Polyp Closure and Visual Outcome in Polypoidal Choroidal Vasculopathy using Artificial Intelligence”.
  Prof Gemmy Cheung; S$100,000.00

• “Functional Role of human embryonic stem cell derived photoreceptor progenitors in non-human primates”.
  Dr Gavin Tan; S$30,000.00

• “Randomised placebo controlled study of herbal medication to treat dry eye in peri/ post-menopausal women”.
  A/Prof Louis Tong; S$415,224.75

• “The role of Caveolin-1 in Ocular Neurovascular Coupling”.
  Dr Rachel Chong; S$20,000.00

• “Translating MSC exosomes into pharmaceuticals (TEx2Pharm)”.
  Prof Jodhbir Mehta & Dr Ong Hon Shing; S$1,032,585.00

• “Implementation of Community-based Elderly Health Care for Eye and Systemic Diseases Using Automated screening”.
  Dr Tyler Rim Hyungtaek; S$375,000.00

• “Transforming vision evaluation and dilation in the care of ophthalmic patients”.
  Dr Gavin Tan; S$49,999.20

SingHealth

• “Artificial Intelligence for Functional VIsion Screening Using Retinal Imaging (AVIRI)”.
  Dr Tham Yih Chung; S$100,000.00

• “From Machine to Machine - Developing a Deep Learning Algorithm for Quantification of Ocular Traits based on Retinal Photographs”.
  Dr Tyler Rim Hyungtaek; S$100,000.00

• “COVID-19 Pandemic: Triaging of ‘Only Urgent Eye Referrals’ from Polyclinics (TOP) using Retinal Photograph-based Deep Learning”.
  Dr Tham Yih Chung; S$28,500.00

• “Choroidal All-trans Retinoic Acid Involvement in the Local Control of Eye Growth in Myopia  Development”.
  Dr Jiang Liqin; S$49,500.00

• “The Role of the Aging Visual Function System on Functional Health in Elderly  Singaporeans”.
  Dr Preeti Gupta; S$149,889.00

• “Task Shifting intravitreal Injection from Ophthalmologists to Nurses: A Prospective Randomized Non-Inferiority Trial”.
  A/Prof Ian Yeo; S$65,000.00

Commercial

• “Correlating pathological optical coherence tomography changes in age related macular degeneration with functional visual losses measured on microperimetry.”.
  Dr Anna Tan; S$95,136.66

• “SinSa Labs Combination Antibiotic Study”.
  A/Prof Rajamani Lakshminarayanan; S$103,530.74

• “A Randomized, Double-masked, Sham-controlled Phase 4 Study of the Efficacy, Safety and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept with Adjunctive Photodynamic Therapy in patients with Polypoidal Choroidal Vasculopathy (ATLANTIC)”.
  A/Prof Cheng Ching Yu; S$21,000.00

• “A Phase III, Multicenter, Randomized, Double-masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients with Neovascular Age-Related Macular Degeneration (Lucerne)”.
  Prof Gemmy Cheung; S$281,164.60

• “Testing efficacy and toxicity of DcB in spontaneous ocular hypertensive monkeys”.
  Dr Amutha Barathi; S$139,010.28

• “A Comparative Clinical Evaluation of a New Tecnis® Presbyopia-Correcting Intraocular Lens Against a Trifocal Intraocular Lens”.
  A/Prof Chee Soon Phaik; S$129,391.43

• “Testing small molecule compound in Mice CNV model”.
  Dr Amutha Barathi; S$71,362.47

• “Efficacy of Retrobulbar Latanoprost on Orbital Fat in Rat Model”.
  Dr Amutha Barathi; S$61,765.96

• “A Multicenter, Double-Masked, Randomized, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Conbercept Intravitreal Injection in Subjects with Neovascular Age-related Macular Degeneration”.
  Dr Kelvin Teo; S$205,871.75

• “Assessment of Various Dyes on Cultured Primary Human Corneal Endothelial Cells (2020)”.
  Prof Jodhbir Mehta; S$24,551.15

• “Determination of the Ocular Tissue Distribution of EXN407 After a Repeated Topical Ocular Dose Regimen in Cynomolgus Monkeys”.
  Dr Amutha Barathi; S$666,083.13

• “Ophthalmology-Related Biomarkers Validation Using Persistent Retinal Neovascularization Rabbit Models Induced by Intravitreal Injection of DL-α-aminoadipic acid (AAA)”.
  Dr Amutha Barathi; S$10,289.00