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Dr Jacqueline Chua

Dr Chua Jacqueline

​BOptom, PhD, FAAO

Academic Appointments

  • Assistant Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


Dr Jacqueline Chua is a Clinician Scientist at Singapore Eye Research Institute and a practicing Optometrist at the Singapore National Eye Centre at a primary eye care setting. Dr Chua graduated with a Bachelor of Optometry from the University of Melbourne and a PhD from the University of Auckland. Upon completion of her doctorate, she undertook a five-year stint in optometric academia. She has also attained a clinical fellowship from the American Academy of Optometry. She was recently awarded the Transition Award, an early career talent development fund for clinician scientists to improve the detection of glaucoma using new imaging technology.


  • FAAO (2015)
  • PhD (2008)
  • BOptom (2001)

Professional Appointments and Committee Memberships

  • Co-Vice Chair of Research Mentoring and Research Training & Development, Allied Health Research Committee, Singapore General Hospital (2017 – present)
  • Member, Clinical Optometry Practice Advisory Panel – Implementation Workgroup, Ministry of Health (2017 – present)
  • Member, Accreditation Committee, Optometrists and Opticians Board (2017 – present)
  • Fellow, American Academy of Optometry, USA (2015 – present)
  • Member, New Zealand Association of Optometrists, New Zealand (2014 – present)
  • Member, Association for Research Vision and Ophthalmology (ARVO), USA (2013 – present)


  • SingHealth Publication Award for Allied Health, Singapore (2019, 2018)
  • VisionSave Future-Focused Education Award, Singapore (2018)
  • Best light microscopy winner in imaging competition, School of Medical Sciences, University of Auckland, New Zealand (2008)
  • New Zealand save sight society grant for postdoctoral research (2008)
  • New Zealand Health Research Council and Retina Australia Scholarship for PhD (2003)

Research Interests

  • Ocular Imaging
  • Primary eye care
  • Epidemiology


  1. Yao X, Ke M, Ho Y, Lin E, Wong DWK, Tan B, Schmetterer L, Chua J. Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope. Br J Ophthalmol 2020.

  2. Lin E, Ke M, Tan B, Yao X, Wong D, Ong L, Schmetterer L, Chua J. Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study. Sci Rep 2020;10(1):11249.

  3. Chua J, Sim R, Tan B, Wong D, Yao X, Liu X, Ting DSW, Schmidl D, Ang M, Garhöfer G, Schmetterer L. Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy. J Clin Med 2020;9(6).

  4. Chua J, Schwarzhans F, Nguyen DQ, Tham YC, Sia JT, Lim C, Mathijia S, Cheung C, Tin A, Fischer G, Cheng CY, Vass C, Schmetterer L. Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders. Br J Ophthalmol 2020;104(2):282-90.

  5. Chua J, Kadziauskienė A, Wong D, Ašoklis R, Lesinskas E, Quang ND, Chong R, Tan B, Girard MJA, Mari JM, Crowston JG, Aung T, Schmetterer L. One year structural and functional glaucoma progression after trabeculectomy. Sci Rep 2020;10(1):2808.

  6. Chua J, Tham YC, Tan B, Devarajan K, Schwarzhans F, Gan A, Wong D, Cheung CY, Majithia S, Thakur S, Fischer G, Vass C, Cheng CY, Schmetterer L. Age-related changes of individual macular retinal layers among Asians. Sci Rep 2019;9(1):20352.

  7. Chua J, Tan B, Ang M, Nongpiur ME, Tan AC, Najjar RP, Milea D, Schmetterer L. Future clinical applicability of optical coherence tomography angiography. Clin Exp Optom 2019;102(3):260-9.

  8. Chua J, Chin CWL, Tan B, Wong SH, Devarajan K, Le TT, Ang M, Wong TY, Schmetterer L. Impact of systemic vascular risk factors on the choriocapillaris using optical coherence tomography angiography in patients with systemic hypertension. Sci Rep 2019;9(1):5819.

  9. Chua J, Chin CWL, Hong J, Chee ML, Le TT, Ting DSW, Wong TY, Schmetterer L. Impact of hypertension on retinal capillary microvasculature using optical coherence tomographic angiography. J Hypertens 2019;37(3):572-80.

  10. Chua J, Chee ML, Chin CWL, Tham YC, Tan N, Lim SH, Aung T, Cheng CY, Wong TY, Schmetterer L. Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study. Br J Ophthalmol 2019;103(2):196-202.

  11. Chua J, Lim CXY, Wong TY, Sabanayagam C. Diabetic Retinopathy in the Asia-Pacific. Asia Pac J Ophthalmol (Phila) 2018;7(1):3-16.

  12. Chua J, Chia AR, Chee ML, Man REK, Tan GSW, Lamoureux EL, Wong TY, Chong MF, Schmetterer L. The relationship of dietary fish intake to diabetic retinopathy and retinal vascular caliber in patients with type 2 diabetes. Sci Rep 2018;8(1):730.

  13. Koh V, Chua J, Shi Y, Thakku SG, Lee R, Nongpiur ME, Baskaran M, Kumar RS, Perera S, Aung T, Cheng CY. Association of iris crypts with acute primary angle closure. Br J Ophthalmol 2017;101(10):1318-22.

  14. Chua J, Thakku SG, Pham TH, Lee R, Tun TA, Nongpiur ME, Tan MCL, Wong TY, Quah JHM, Aung T, Girard MJA, Cheng CY. Automated Detection of Iris Furrows and their Influence on Dynamic Iris Volume Change. Sci Rep 2017;7(1):17894.

  15. Chua J, Nongpiur ME, Zhao W, Tham YC, Gupta P, Sabanayagam C, Aung T, Wong TY, Cheng CY. Comparison of Corneal Biomechanical Properties between Indian and Chinese Adults. Ophthalmology 2017;124(9):1271-9.

  16. Chua J, Lim B, Fenwick EK, Gan AT, Tan AG, Lamoureux E, Mitchell P, Wang JJ, Wong TY, Cheng CY. Prevalence, Risk Factors, and Impact of Undiagnosed Visually Significant Cataract: The Singapore Epidemiology of Eye Diseases Study. PLoS One 2017;12(1):e0170804.

  17. Chua J, Thakku SG, Tun TA, Nongpiur ME, Tan MC, Girard MJ, Wong TY, Quah JH, Aung T, Cheng CY. Iris Crypts Influence Dynamic Changes of Iris Volume. Ophthalmology 2016;123(10):2077-84.

  18. Chua J, Koh JY, Tan AG, Zhao W, Lamoureux E, Mitchell P, Wang JJ, Wong TY, Cheng CY. Ancestry, Socioeconomic Status, and Age-Related Cataract in Asians: The Singapore Epidemiology of Eye Diseases Study. Ophthalmology 2015;122(11):2169-78.

  19. Chua J, Baskaran M, Ong PG, Zheng Y, Wong TY, Aung T, Cheng CY. Prevalence, Risk Factors, and Visual Features of Undiagnosed Glaucoma: The Singapore Epidemiology of Eye Diseases Study. JAMA Ophthalmol 2015;133(8):938-46.

  20. Chua J, Tham YC, Liao J, Zheng Y, Aung T, Wong TY, Cheng CY. Ethnic differences of intraocular pressure and central corneal thickness: the Singapore Epidemiology of Eye Diseases study. Ophthalmology 2014;121(10):2013-22.

Research Trials

  • ​Provide modern imaging devices to the four major clinical eye centres in Singapore to perform multi-centre trials within Singapore (2017 – present)
  • Acquire novel imaging technologies to conduct high-level research in the field of blinding-forms of eye diseases (2017 – present)
  • Design and build a unique high-resolution, full range anterior segment imaging system (2017 – present)
  • Development of novel imaging parameters for clinical use (2017 – present)