Profile
Dr Aihua Hou graduated in 1999 with bachelor degree in major of Microbiology from Huazhong Agriculture University, China. She continued the training in Microbiology and attained Master degree from Shandong University, China in 2002. She completed her Ph.D. training in human genetics at Nanyang Technological University, Singapore with NTU’s scholarship from 2003 to 2008. After 2 years of postdoctoral training in NTU, Dr Hou joined SERI in 2010.
Professional Appointments and Committee Memberships
- Member, The Association for Research in Vision and Ophthalmology (2012)
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Awards
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Teaching assistant scholarship, Nanyang Technological University, Singapore (2005)
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Research Scholarship, Nanyang Technological University, Singapore (2003 – 2008)
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Guanghua Fellowship, Shandong University, China (2002)
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Research Interests
- Dry eye
- Ocular surface inflammation
- Corneal wound healing
- Pterygium disease
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Publications
Altered expression level of inflammation-related genes and long-term changes in ocular surface after trabeculectomy, a prospective cohort study. Tong L, Hou AH, Wong TT. Ocul Surf. 2018 Oct;16(4):441-447.
Topical Delivery of Senicapoc Nanoliposomal Formulation for Ocular Surface Treatments. Phua JL, Hou A, Lui YS et al. Int J Mol Sci. 2018 Sep 29;19(10).
A chronic autoimmune dry eye rat model with increase in effector memory T cells in eyeball tissue. Hou Aihua, Bose T, Chandy KG, Tong L. J Vis Exp. 2017 Jun 7;(124)
Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease. Bose T, Lee R, Hou Aihua, Tong L, Chandy KG. Sci Rep. 2017 Mar 27;7:45312
In vitro secretomics study of pterygium-derived fibroblasts by iTRAQ-based quantitative proteomics strategy. Hou Aihua, Law KP, Tin MQ, Lim YP, Tong L. Exp Eye Res. 2016 Dec;153:14-22
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Research Trials
- Investigating the efficacy and safety of OAHFA eye drops as an over-the-counter supplement to prevent dry eye (2016 – present)
- Developing anti-inflammation eye drops targeting T cells (2015 – present
- Profiling immune cell populations and comparing gene expression differences in ocular surface of patients with different autoimmune diseases (2015 – present)
- Identifying new treatment targets for pterygium disease by exploring the phosphoproteomics of pterygium fibroblast cells (2013 – present)
- Studying the interaction of transglutaminase 2 (TG2) and tight junction proteins during corneal wound healing (2012 – 2017)
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