Profile
Dr Jayaraman is a Senior Research Fellow at NNI and Executive Director of ASEAN Microbiome Nutrition Centre, NNI. Dr Jayaraman’s research focuses on understanding the role of gut microbiota in healthy aging and disease, with particular focus on gut-brain axis. At NNI, under AMNC, Dr Jayaraman is using animal models, behavioural and molecular techniques to answer research questions pertaining to the role of gut-brain communication in neurodegenerative, neurological, and metabolic disorders, with the goal to translate research evidence to clinical practice.
Education
- PhD, Neuroscience – University of Southern California, USA
- MS, Biological Science – UMASS Medical Center, USA
- B.Sc, Microbiology – Bangalore University, India
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Professional Appointments and Committee Memberships
- Executive Director, ASEAN Microbiome Nutrition Centre
- Senior Research Fellow I, Research, National Neuroscience Institute
- Society for Neuroscience
- ISTAART – Alzheimer’s Association
- Editorial Board member, Frontiers in Aging Neuroscience
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Awards
- Young Investigator Award, 7th International Meeting of Steroids and Nervous System, Torino, Italy
- Postdoctoral Scholar Travel and Training Grant, USC Office of Postdoctoral Affairs, University of Southern California, CA
- Travel Fellowship Grant for Postdoctoral scientists, International Brain Research Organization (IBRO)
- WiSE Grant – Women in Science and Engineering (WiSE), University of Southern California, CA
- Women in Science and Engineering Fellowship – Women in Science and Engineering (WiSE), University of Southern California, CA
- Best Student Merit Award, USC Office of International Students
- Joint Initiative Graduate Merit Award, University of Southern California, CA
- Neuroscience Advisory Group Stipend Top-off Award, University of Southern California, CA
- Summer Fellowship, National Academy of Science, India
- National Talent Search Scholarship, NCERT, New Delhi, India
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Research Interests
- Gut brain communication
- Neurodegenerative diseases
- Metabolic disorders
- Anxiety and mood disorders
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Publications
- Jayaraman A*, Pettersson, S. When dysbiosis meets dystrophy: an unwanted gut-muscle connection.. EMBO Mol Med (2023) e17324. https://doi.org/10.15252/emmm.202217324
- Melby, M.K., Tharmabalan, R.T., Sällberg Chen, M., Pettersson, S., Jayaraman, A*. (2023). Gut Microbes: Gateway to Reshaping Biological Aging. In: Handbook of Aging, Health and Public Policy. Springer, Singapore. https://doi.org/10.1007/978-981-16-1914-4_176-1
- Verma NK, Naik RR, Han SWB, Jayaraman A, Fazil MHT, Kai YL, Mei SC, Chen XY, Khoo YT, Mamidi A, Lakshminarayanan R, Lai KO, Wong JH, Fairley LH, Anselm V, Zi QL, Verma R, Barron AM. Autoimmune and Autoinflammatory Neurologic Disorders. Translational Neuroimmunology vol 7; 2022. (Book Chapter) (In Press)
- Fairley LH, Lai KO, Wong JH, Chong WJ, Vincent AS, D'Agostino G, Wu X, Naik RR, Jayaraman A, Langley SR, Ruedl C, Barron AM. Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2209177120. doi: 10.1073/pnas.2209177120.
- Jayaraman A*, Pettersson S. Happy ageing by trusting our gut microbes. BBRC Invited Mini review 2022; 633:88-91. https://doi.org/10.1016/j.bbrc.2022.09.026.
- Jayaraman A*, Reynolds R. Diverse pathways to neuronal necroptosis in Alzheimer’s disease. Eur J Neurosci. 2022; 56(9):5428-5441. doi: 10.1111/ejn.15662.
Refer to Google Scholar for full list of publications: https://scholar.google.com/citations?user=AAKtUCEAAAAJ&hl=en&oi=ao
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